{"Name":"Anodontia","DiseaseID__c":"GARD:0005818","id":5818,"encodedName":"anodontia","IsDeleted":false,"Disease_Name_Full__c":"Anodontia","Xref_IDs__c":"16958000; 26624006; C0399352; D000848; DOID:13714; HP:0000674; MEDGEN:98313; MONDO:0008797; OMIM:206780; ORPHA:99797","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":4,"Disease_Characteristics_Score__c":6,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0008797","Disease_Description__c":"An extreme developmental dental anomaly characterized by the complete absence of all teeth.","GARD_Name__c":"Anodontia","GARD_Synonym__c":"agomphiasis; agomphosis; anodontia vera; anodontism; complete absence of teeth; complete agenesis of all teeth; complete anodontia; complete congenital absence of teeth; complete dental agenesis; congenital absence of teeth; congenital edentia; developmental absence of tooth; failure of development of all teeth; missing all teeth; total absence of all teeth; total anodontia; total anodontia of permanent and deciduous teeth","Curated_Disease_Description_Source__c":"GARD:0005818","Curated_Disease_Description__c":"Anodontia is a dental condition characterized by complete absence of teeth. The primary (baby) or permanent (adult) teeth may be involved. In most cases, the condition is associated with a group of conditions called the ectodermal dysplasias. In these cases, abnormalities are also noted in the hair, nails, and sweat glands. Anodontia is an autosomal recessive condition.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:99797","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0008797","ORPHANET_ID__c":"ORPHA:99797","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Anodoncia","Spanish_Description_Source__c":"ORPHA:99797","Spanish_Description__c":"Es una anomalía extrema del desarrollo dental caracterizada por la ausencia total de dientes.","Spanish_Disease_Name__c":"anodoncia","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:98026","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Anodontia is a dental condition characterized by complete absence of teeth. The primary (baby) or permanent (adult) teeth may be involved. In most cases, the condition is associated with a group of conditions called the ectodermal dysplasias. In these cases, abnormalities are also noted in the hair, nails, and sweat glands. Anodontia is an autosomal recessive condition.","Curated_Disease_Description_Source__c":"GARD:0005818","GARD_Synonym__c":"agomphiasis; agomphosis; anodontia vera; anodontism; complete absence of teeth; complete agenesis of all teeth; complete anodontia; complete congenital absence of teeth; complete dental agenesis; congenital absence of teeth; congenital edentia; developmental absence of tooth; failure of development of all teeth; missing all teeth; total absence of all teeth; total anodontia; total anodontia of permanent and deciduous teeth","Name":"Anodontia","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"National Foundation for Ectodermal Dysplasias","Website__c":"https://www.nfed.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Genetics","Tag_Category__c":"Cause;Disease Category;Specialist","category_description":"Genetic diseases affect the DNA, or genetic instructions, which directs how tissues, organs, and body systems function.","curated_tag_name":"Genetic diseases"},{"Tag_Name__c":"Odontology","Tag_Category__c":"Specialist"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=16958000","Source__c":"MONDO:0008797","Xref__c":"16958000"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=98313","Source__c":"C0399352","Xref__c":"MEDGEN:98313"},{"URL__c":"https://www.orpha.net/en/disease/detail/99797","Source__c":"C0399352; MONDO:0008797; ORPHA:99797","Xref__c":"ORPHA:99797"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C000848","Source__c":"MONDO:0008797","Xref__c":"D000848"},{"URL__c":"https://www.omim.org/entry/206780","Source__c":"MONDO:0008797; ORPHA:99797","Xref__c":"OMIM:206780"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A13714","Source__c":"MONDO:0008797","Xref__c":"DOID:13714"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0399352","Source__c":"C0399352","Xref__c":"C0399352"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0000674","Source__c":"C0399352","Xref__c":"HP:0000674"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0008797","Source__c":"GARD:0005818","Xref__c":"MONDO:0008797"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=26624006","Source__c":"C0399352","Xref__c":"26624006"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=234951001","Source__c":"C0399352","Xref__c":"234951001"}],"Inheritance__c":["Autosomal recessive"],"GARD_Disease_Feature__c":[{"Provided_By__c":"OMIM:206780","Feature__r":{"HPO_Description__c":"The absence of all teeth from the normal series by a failure to develop.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0000674","HPO_Synonym__c":"Anodontia vera; Complete agenesis of all teeth; Complete dental agenesis; Failure of development of all teeth","HPO_Name__c":"Anodontia","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Cause":["Genetics"],"Disease Category":["Genetics"],"Specialist":["Genetics","Odontology"]},"synonyms":["agomphiasis"," agomphosis"," anodontia vera"," anodontism"," complete absence of teeth"," complete agenesis of all teeth"," complete anodontia"," complete congenital absence of teeth"," complete dental agenesis"," congenital absence of teeth"," congenital edentia"," developmental absence of tooth"," failure of development of all teeth"," missing all teeth"," total absence of all teeth"," total anodontia"," total anodontia of permanent and deciduous teeth"]}