{"Name":"Atrophoderma of Pierini and Pasini","DiseaseID__c":"GARD:0005866","id":5866,"encodedName":"atrophoderma-of-pierini-and-pasini","IsDeleted":false,"Disease_Name_Full__c":"Atrophoderma of Pierini and Pasini","Xref_IDs__c":"711524008; C3887897; L90.3; MEDGEN:854615; MONDO:0022513; ORPHA:658810","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0022513","Disease_Description__c":"Atrophoderma of Pierini and Pasini is thought to possibly represent a late stage of morphea a type of localized scleroderma. Signs and symptoms ofatrophoderma of Pierini and Pasini include multiple oval, darkened (hyperpigmented) plaques in which tissue under the skin breaks downso that there is a depression (dent) within the skin. Some findings suggest that atrophoderma of Pierini and Pasini may be associated with B burgdorferi, a bacteria that causesLyme disease, in some cases.","GARD_Name__c":"Atrophoderma of Pierini and Pasini","GARD_Synonym__c":"atrophoderma of pasini and pierini; idiopathic atrophoderma of pasini and pierini","Curated_Disease_Description_Source__c":"GARD:0005866","Curated_Disease_Description__c":"Atrophoderma of Pasini and Pierini (ATPP) is a rare skin condition that results in patchy areas of discolored skin. The main symptom of Atrophoderma of Pasini and Pierini is multiple irregularly shaped, dark or light areas of skin in which the tissue under the skin breaks down resulting in a depression (dent). The cause of ATPP is unknown. Diagnosis is based on clinical examination and a skin biopsy.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0022513","ORPHANET_ID__c":"ORPHA:658810","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Atrofodermia de pasini y pierini","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"atrofodermia de pasini y pierini","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:89826","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Atrophoderma of Pasini and Pierini (ATPP) is a rare skin condition that results in patchy areas of discolored skin. The main symptom of Atrophoderma of Pasini and Pierini is multiple irregularly shaped, dark or light areas of skin in which the tissue under the skin breaks down resulting in a depression (dent). The cause of ATPP is unknown. Diagnosis is based on clinical examination and a skin biopsy.","Curated_Disease_Description_Source__c":"GARD:0005866","GARD_Synonym__c":"atrophoderma of pasini and pierini; idiopathic atrophoderma of pasini and pierini","Name":"Atrophoderma of Pierini and Pasini","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"National Scleroderma Foundation","Website__c":"https://www.scleroderma.org"},{"Account_Name__c":"Scleroderma Research Foundation","Website__c":"https://srfcure.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Dermatology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Skin diseases, or integumentary system diseases, affect the skin, hair, nails, sweat glands, or oil glands.","curated_tag_name":"Skin diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:658810"}],"External_Identifier_Disease__c":[{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/L90.3","Source__c":"MONDO:0022513","Xref__c":"L90.3"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C3887897","Source__c":"C3887897","Xref__c":"C3887897"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=854615","Source__c":"C3887897","Xref__c":"MEDGEN:854615"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=711524008","Source__c":"C3887897; MONDO:0022513","Xref__c":"711524008"},{"URL__c":"https://www.orpha.net/en/disease/detail/658810","Source__c":"MONDO:0022513","Xref__c":"ORPHA:658810"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0022513","Source__c":"GARD:0005866","Xref__c":"MONDO:0022513"}],"tags":{"Account":["Dermatology"],"Disease Category":["Dermatology"],"Specialist":["Dermatology"]},"synonyms":["atrophoderma of pasini and pierini"," idiopathic atrophoderma of pasini and pierini"]}