{"Name":"Localized lipodystrophy","DiseaseID__c":"GARD:0005867","id":5867,"encodedName":"localized-lipodystrophy","IsDeleted":false,"Disease_Name_Full__c":"Localized lipodystrophy","Xref_IDs__c":"788978004; C131814; C4329999; MEDGEN:1385527; MONDO:0019194; ORPHA:79088","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0019194","Disease_Description__c":"A rare group of acquired lipodystrophies that are characterized by loss of subcutaneous tissue from generally small regions of the body, either single or multiple areas, and are not typically associated with metabolic complications. Some cases may involve lipohypertrophy (insulin). This group includes pressure-induced localized lipoatrophy, drug-induced localized lipodystrophy, panniculitis- induced localized lipodystrophy, centrifugal lipodystrophy, and idiopathic localized lipodystrophy.","GARD_Name__c":"Localized lipodystrophy","GARD_Synonym__c":"focal lipodystrophy","Curated_Disease_Description_Source__c":"MONDO:0019194","Curated_Disease_Description__c":"A rare group of acquired lipodystrophies that are characterized by loss of subcutaneous tissue from generally small regions of the body, either single or multiple areas, and are not typically associated with metabolic complications. Some cases may involve lipohypertrophy (insulin). This group includes pressure-induced localized lipoatrophy, drug-induced localized lipodystrophy, panniculitis- induced localized lipodystrophy, centrifugal lipodystrophy, and idiopathic localized lipodystrophy.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:79088","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0019194","ORPHANET_ID__c":"ORPHA:79088","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Lipodistrofias localizadas","Spanish_Description_Source__c":"ORPHA:79088","Spanish_Description__c":"Es un grupo poco frecuente de lipodistrofias adquiridas caracterizadas por la pérdida de tejido subcutáneo de regiones generalmente pequeñas del cuerpo, áreas únicas o múltiples, y que por lo general no están asociadas a complicaciones metabólicas. Algunos casos pueden implicar lipohipertrofia (insulina). Este grupo incluye la lipoatrofia localizada inducida por presión, la lipodistrofia localizada inducida por fármacos, la lipodistrofia localizada inducida por paniculitis, la lipodistrofia centrífuga y la lipodistrofia localizada idiopática.","Spanish_Disease_Name__c":"lipodistrofias localizadas","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:97978","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare group of acquired lipodystrophies that are characterized by loss of subcutaneous tissue from generally small regions of the body, either single or multiple areas, and are not typically associated with metabolic complications. Some cases may involve lipohypertrophy (insulin). This group includes pressure-induced localized lipoatrophy, drug-induced localized lipodystrophy, panniculitis- induced localized lipodystrophy, centrifugal lipodystrophy, and idiopathic localized lipodystrophy.","Curated_Disease_Description_Source__c":"MONDO:0019194","GARD_Synonym__c":"focal lipodystrophy","Name":"Localized lipodystrophy","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Lipodystrophy United","Website__c":"https://www.lipodystrophyunited.org"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Endocrine","Tag_Category__c":"Disease Category;Specialist","category_description":"Endocrine diseases affect hormone production or how the body responds to a specific hormone(s).","curated_tag_name":"Endocrine diseases"},{"Tag_Name__c":"Dermatology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Skin diseases, or integumentary system diseases, affect the skin, hair, nails, sweat glands, or oil glands.","curated_tag_name":"Skin diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:79088"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C131814","Source__c":"C4329999; MONDO:0019194","Xref__c":"C131814"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1385527","Source__c":"C4329999","Xref__c":"MEDGEN:1385527"},{"URL__c":"https://www.orpha.net/en/disease/detail/79088","Source__c":"C4329999; MONDO:0019194; ORPHA:79088","Xref__c":"ORPHA:79088"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C4329999","Source__c":"C4329999","Xref__c":"C4329999"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019194","Source__c":"GARD:0005867","Xref__c":"MONDO:0019194"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=788978004","Source__c":"C4329999","Xref__c":"788978004"}],"tags":{"Disease Category":["Endocrine","Dermatology"],"Specialist":["Endocrine","Dermatology","Pediatrics"],"Account":["Dermatology"]},"synonyms":["focal lipodystrophy"]}