{"Name":"Balo concentric sclerosis","DiseaseID__c":"GARD:0005885","id":5885,"encodedName":"balo-concentric-sclerosis","IsDeleted":false,"Disease_Name_Full__c":"Balo concentric sclerosis","Xref_IDs__c":"230380005; C0004712; C197875; DOID:0060215; MEDGEN:498; MONDO:0016430; ORPHA:228165","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0016430","Disease_Description__c":"Tumefactive multiple sclerosis is characterized by a tumor-like lesion larger than two centimeters and signs and symptoms similar to those of a brain tumor. It is a rare form of multiple sclerosis (MS). Symptoms of tumefactive MS often differ from other MS cases and may include, headaches, changes in thinking, confusion, speech problems, seizures, and weakness. The cause of tumefactive MS is not known. It often develops into the relapsing-remitting form of MS. In other cases there is only one occurrence of the condition. In still others the disease process remains less clear. While there is no cure for tumefactive MS, treatments such as corticosteroids are available to decrease disease activity.","GARD_Name__c":"Balo concentric sclerosis","GARD_Synonym__c":"balo disease; balo's concentric sclerosis; balos concentric sclerosis; baló concentric sclerosis; concentric demyelination; concentric sclerosis","Curated_Disease_Description_Source__c":"GARD:0005885","Curated_Disease_Description__c":"Baló concentric sclerosis (Tumefactive multiple sclerosis) is characterized by a tumor-like lesion larger than two centimeters and signs and symptoms similar to those of a brain tumor. It is a rare form of multiple sclerosis (MS). Symptoms of Baló concentric sclerosis often differ from other MS cases and may include, headaches, changes in thinking, confusion, speech problems, seizures, and weakness. The cause of Baló concentric sclerosis is not known.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:228165","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0016430","ORPHANET_ID__c":"ORPHA:228165","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Esclerosis concéntrica de baló","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"esclerosis concéntrica de baló","Spanish_GARD_Synonym__c":"desmielinización concéntrica","Category_Linearization__c":"ORPHA:98006","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Baló concentric sclerosis (Tumefactive multiple sclerosis) is characterized by a tumor-like lesion larger than two centimeters and signs and symptoms similar to those of a brain tumor. It is a rare form of multiple sclerosis (MS). Symptoms of Baló concentric sclerosis often differ from other MS cases and may include, headaches, changes in thinking, confusion, speech problems, seizures, and weakness. The cause of Baló concentric sclerosis is not known.","Curated_Disease_Description_Source__c":"GARD:0005885","GARD_Synonym__c":"balo disease; balo's concentric sclerosis; balos concentric sclerosis; baló concentric sclerosis; concentric demyelination; concentric sclerosis","Name":"Balo concentric sclerosis","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Autoimmune Registry","Website__c":"https://www.autoimmuneregistry.org/"},{"Account_Name__c":"Global Autoimmune Institute","Website__c":"https://www.autoimmuneinstitute.org/"},{"Account_Name__c":"Accelerated Cure Project","Website__c":"https://www.acceleratedcure.org/"},{"Account_Name__c":"Multiple Sclerosis Association of America","Website__c":"https://mymsaa.org/"},{"Account_Name__c":"Multiple Sclerosis Foundation","Website__c":"https://msfocus.org/"},{"Account_Name__c":"National Multiple Sclerosis Society","Website__c":"https://www.nationalmssociety.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:228165"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=498","Source__c":"C0004712","Xref__c":"MEDGEN:498"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0004712","Source__c":"C0004712","Xref__c":"C0004712"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A0060215","Source__c":"MONDO:0016430","Xref__c":"DOID:0060215"},{"URL__c":"https://www.orpha.net/en/disease/detail/228165","Source__c":"C0004712; MONDO:0016430; ORPHA:228165","Xref__c":"ORPHA:228165"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=230380005","Source__c":"C0004712; MONDO:0016430","Xref__c":"230380005"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0016430","Source__c":"GARD:0005885","Xref__c":"MONDO:0016430"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C197875","Source__c":"C0004712","Xref__c":"C197875"}],"Inheritance__c":["Non-Mendelian inheritance"],"tags":{"Disease Category":["Neurology"],"Specialist":["Neurology"]},"synonyms":["balo disease"," balo's concentric sclerosis"," balos concentric sclerosis"," baló concentric sclerosis"," concentric demyelination"," concentric sclerosis"]}