{"Name":"Intrahepatic cholangiocarcinoma","DiseaseID__c":"GARD:0006042","id":6042,"encodedName":"intrahepatic-cholangiocarcinoma","IsDeleted":false,"Disease_Name_Full__c":"Intrahepatic cholangiocarcinoma","Xref_IDs__c":"109842005; C0345905; C22.1; C35417; DOID:4928; MEDGEN:87521; MONDO:0003210","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0003210","Disease_Description__c":"A carcinoma that arises from the intrahepatic bile duct epithelium in any site of the intrahepatic biliary tree. Grossly, the malignant lesions are solid, nodular, and grayish. Morphologically, the vast majority of cases are adenocarcinomas. Signs and symptoms include malaise, weight loss, right upper quadrant abdominal pain, and night sweats. Early detection is difficult and the prognosis is generally poor.","GARD_Name__c":"Intrahepatic cholangiocarcinoma","GARD_Synonym__c":"cholangiocarcinoma of intrahepatic biliary tract; cholangiocarcinoma, intrahepatic, malignant; icc; intrahepatic bile duct cancer (cholangiocarcinoma); intrahepatic bile duct carcinoma; intrahepatic carcinoma of bile duct; intrahepatic carcinoma of the bile duct; intrahepatic cholangiocarcinoma (bile duct cancer); intrahepatic cholangiocellular carcinoma; peripheral cholangiocarcinoma","Curated_Disease_Description_Source__c":"GARD:0006042","Curated_Disease_Description__c":"Intrahepatic cholangiocarcinoma is a cancer that develops in the cells within the bile ducts; both inside and outside the liver. The terms cholangiocarinoma and bile duct cancer are often used to refer to the same condition. Signs and symptoms of Intrahepatic cholangiocarcinoma include jaundice, abdominal pain, fever, weight loss, weakness and itching.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0003210","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Intrahepatic cholangiocarcinoma is a cancer that develops in the cells within the bile ducts; both inside and outside the liver. The terms cholangiocarinoma and bile duct cancer are often used to refer to the same condition. Signs and symptoms of Intrahepatic cholangiocarcinoma include jaundice, abdominal pain, fever, weight loss, weakness and itching.","Curated_Disease_Description_Source__c":"GARD:0006042","GARD_Synonym__c":"cholangiocarcinoma of intrahepatic biliary tract; cholangiocarcinoma, intrahepatic, malignant; icc; intrahepatic bile duct cancer (cholangiocarcinoma); intrahepatic bile duct carcinoma; intrahepatic carcinoma of bile duct; intrahepatic carcinoma of the bile duct; intrahepatic cholangiocarcinoma (bile duct cancer); intrahepatic cholangiocellular carcinoma; peripheral cholangiocarcinoma","Name":"Intrahepatic cholangiocarcinoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Cholangiocarcinoma Foundation","Website__c":"https://cholangiocarcinoma.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=109842005","Source__c":"C0345905; MONDO:0003210","Xref__c":"109842005"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=87521","Source__c":"C0345905","Xref__c":"MEDGEN:87521"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C35417","Source__c":"C0345905; MONDO:0003210","Xref__c":"C35417"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0345905","Source__c":"C0345905","Xref__c":"C0345905"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A4928","Source__c":"MONDO:0003210","Xref__c":"DOID:4928"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0003210","Source__c":"GARD:0006042","Xref__c":"MONDO:0003210"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=1260050006","Source__c":"C0345905","Xref__c":"1260050006"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/C22.1","Source__c":"MONDO:0003210","Xref__c":"C22.1"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["cholangiocarcinoma of intrahepatic biliary tract"," cholangiocarcinoma, intrahepatic, malignant"," icc"," intrahepatic bile duct cancer (cholangiocarcinoma)"," intrahepatic bile duct carcinoma"," intrahepatic carcinoma of bile duct"," intrahepatic carcinoma of the bile duct"," intrahepatic cholangiocarcinoma (bile duct cancer)"," intrahepatic cholangiocellular carcinoma"," peripheral cholangiocarcinoma"]}