{"Name":"Chondrosarcoma","DiseaseID__c":"GARD:0006055","id":6055,"encodedName":"chondrosarcoma","IsDeleted":false,"Disease_Name_Full__c":"Chondrosarcoma","Xref_IDs__c":"1163016002; 443520009; C0008479; C2946; D002813; DOID:3371; HP:0006765; MEDGEN:3054; MONDO:0008977; OMIM:215300; ORPHA:55880","USA_Estimate__c":"50,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"80,000 to 800,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0008977","Disease_Description__c":"A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.","GARD_Name__c":"Chondrosarcoma","GARD_Synonym__c":"chondrosarcoma (disease); chondrosarcoma, malignant; chondrosarcoma, somatic; chondrosarcoma, somatic mutation; fibrochondrosarcoma","Curated_Disease_Description_Source__c":"MONDO:0008977","Curated_Disease_Description__c":"A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"50,000","Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:55880","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0008977","ORPHANET_ID__c":"ORPHA:55880","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Condrosarcoma","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"condrosarcoma","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A malignant cartilaginous matrix-producing mesenchymal neoplasm arising from the bone and soft tissue. It usually affects middle-aged to elderly adults. The pelvic bones, ribs, shoulder girdle, and long bones are the most common sites of involvement. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion.","Curated_Disease_Description_Source__c":"MONDO:0008977","GARD_Synonym__c":"chondrosarcoma (disease); chondrosarcoma, malignant; chondrosarcoma, somatic; chondrosarcoma, somatic mutation; fibrochondrosarcoma","Name":"Chondrosarcoma","Curated_USA_Estimate__c":"50,000","estimateUsa":"50,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Sarcoma UK","Website__c":"https://sarcoma.org.uk/"},{"Account_Name__c":"Sarcoma Foundation of America","Website__c":"https://www.curesarcoma.org/"},{"Account_Name__c":"American Cancer Society","Website__c":"https://www.cancer.org"},{"Account_Name__c":"The Limb Preservation Foundation","Website__c":"http://limbpreservation.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Orthopedics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:55880"}],"Diagnosis__c":[{"Type__c":"GTR","Curie__c":"MEDGEN:C0008479"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0006055","Source__c":"RareSource"},{"URL__c":"https://www.omim.org/entry/215300","Source__c":"C0008479; MONDO:0008977; ORPHA:55880","Xref__c":"OMIM:215300"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0008479","Source__c":"C0008479","Xref__c":"C0008479"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=443520009","Source__c":"C0008479; MONDO:0008977","Xref__c":"443520009"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A3371","Source__c":"MONDO:0008977","Xref__c":"DOID:3371"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C2946","Source__c":"C0008479; MONDO:0008977","Xref__c":"C2946"},{"URL__c":"https://www.orpha.net/en/disease/detail/55880","Source__c":"C0008479; MONDO:0008977; ORPHA:55880","Xref__c":"ORPHA:55880"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C002813","Source__c":"C0008479; MONDO:0008977","Xref__c":"D002813"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=3054","Source__c":"C0008479","Xref__c":"MEDGEN:3054"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0008977","Source__c":"GARD:0006055","Xref__c":"MONDO:0008977"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0006765","Source__c":"C0008479","Xref__c":"HP:0006765"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=1163016002","Source__c":"C0008479","Xref__c":"1163016002"}],"GARD_Disease_Gene__c":[{"GeneSymbol__c":"EXT1","GHR_URL__c":"https://medlineplus.gov/genetics/gene/ext1","Gene_Type__c":"protein-coding gene","Causal_Gene__c":true}],"GARD_Disease_Feature__c":[{"Provided_By__c":"OMIM:215300","Feature__r":{"HPO_Description__c":"A slowly growing malignant neoplasm derived from cartilage cells.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0006765","HPO_Name__c":"Chondrosarcoma","Feature_System__c":"Musculoskeletal System","HPO_Feature_Type__c":"Symptom"}}],"tags":{"Specialist":["Cancer - Oncologist","Orthopedics"],"Disease Category":["Cancer"]},"synonyms":["chondrosarcoma (disease)"," chondrosarcoma, malignant"," chondrosarcoma, somatic"," chondrosarcoma, somatic mutation"," fibrochondrosarcoma"]}