{"Name":"Cystic hygroma","DiseaseID__c":"GARD:0006234","id":6234,"encodedName":"cystic-hygroma","IsDeleted":false,"Disease_Name_Full__c":"Cystic hygroma","Xref_IDs__c":"399882002; C0206620; C3724; D018191; DOID:3081; HP:0000476; MEDGEN:60195; MONDO:0009761; OMIM:257350","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":1,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0009761","Disease_Description__c":"A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels.","GARD_Name__c":"Cystic hygroma","GARD_Synonym__c":"cystic hygroma of the neck; cystic lymphangioma; hygroma","Curated_Disease_Description_Source__c":"MONDO:0009761","Curated_Disease_Description__c":"A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0009761","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A benign lymphatic neoplasm usually arising from the neck and characterized by cystic dilation of the lymphatic vessels.","Curated_Disease_Description_Source__c":"MONDO:0009761","GARD_Synonym__c":"cystic hygroma of the neck; cystic lymphangioma; hygroma","Name":"Cystic hygroma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Birth Defect Research for Children","Website__c":"https://www.birthdefects.org/"},{"Account_Name__c":"Lymphatic Education and Research Network","Website__c":"https://lymphaticnetwork.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Vascular Medicine","Tag_Category__c":"Specialist","curated_tag_name":"Vascular diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=399882002","Source__c":"C0206620; MONDO:0009761","Xref__c":"399882002"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C3724","Source__c":"C0206620; MONDO:0009761","Xref__c":"C3724"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A3081","Source__c":"MONDO:0009761","Xref__c":"DOID:3081"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C018191","Source__c":"C0206620; MONDO:0009761","Xref__c":"D018191"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=60195","Source__c":"C0206620","Xref__c":"MEDGEN:60195"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0206620","Source__c":"C0206620","Xref__c":"C0206620"},{"URL__c":"https://www.omim.org/entry/257350","Source__c":"MONDO:0009761","Xref__c":"OMIM:257350"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=40225001","Source__c":"C0206620","Xref__c":"40225001"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0000476","Source__c":"C0206620","Xref__c":"HP:0000476"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0009761","Source__c":"GARD:0006234","Xref__c":"MONDO:0009761"}],"Inheritance__c":["Autosomal recessive"],"GARD_Disease_Feature__c":[{"Provided_By__c":"OMIM:257350","Feature__r":{"HPO_Description__c":"A cystic lymphatic lesion of the neck.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0000476","HPO_Synonym__c":"Cystic hygroma of the neck","HPO_Name__c":"Cystic hygroma","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"OMIM:257350","Feature__r":{"HPO_Description__c":"The abnormal accumulation of fluid in two or more fetal compartments, including ascites, pleural effusion, pericardial effusion, and skin edema.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0001789","HPO_Name__c":"Hydrops fetalis","HPO_Feature_Type__c":"Symptom"}},{"Provided_By__c":"OMIM:257350","Feature__r":{"HPO_Description__c":"The presence during the prenatal period of a cystic mass with multiple septa with multiple, asymmetric, thin-walled cysts near the posterior aspect of the neck. Fetal cystic hygroma can be defined as nuchal translucency with or without septations measuring greater than 3.0 mm. Increased NT refers to a measurement above the 95th centile, and the term is used irrespective of whether the collection of fluid is septated or not, and whether it is confined to the neck or envelopes the whole fetus. After 14 weeks, increased NT usually resolves, but in some cases it evolves into nuchal edema or cystic hygromas.","HPO_Feature_URL__c":"https://hpo.jax.org/browse/term/HP:0010878","HPO_Name__c":"Fetal cystic hygroma","HPO_Feature_Type__c":"Imaging_Ultrasound_Fetal"}}],"tags":{"Disease Category":["Cancer"],"Specialist":["Vascular Medicine"]},"synonyms":["cystic hygroma of the neck"," cystic lymphangioma"," hygroma"]}