{"Name":"Endometrial stromal sarcoma","DiseaseID__c":"GARD:0006339","id":6339,"encodedName":"endometrial-stromal-sarcoma","IsDeleted":false,"Disease_Name_Full__c":"Endometrial stromal sarcoma","Xref_IDs__c":"1178986006; 423022945; 699356008; C0206630; C8973; D018203; DOID:4226; MEDGEN:60196; MONDO:0006745; ORPHA:213711","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":2,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":2,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0006745","Disease_Description__c":"A malignant mesenchymal neoplasm that affects the uterine corpus, and rarely, the ovaries, cervix, and vagina. In the uterine corpus it is classified as low grade or high grade endometrial stromal sarcoma. In the remainder of the anatomic sites it is classified as low grade endometrioid stromal sarcoma.","GARD_Name__c":"Endometrial stromal sarcoma","GARD_Synonym__c":"endometrial sarcoma; endometrial stromal sarcoma, high grade; endometrial stromal sarcomas; endometrioid stromal sarcoma; ess; sarcomas, endometrial stromal; stromal sarcoma of the corpus uteri; stromal sarcoma, endometrial; stromal sarcoma, endometrial, malignant; stromal sarcomas, endometrial; undifferentiated endometrial sarcoma","Curated_Disease_Description_Source__c":"GARD:0006339","Curated_Disease_Description__c":"Endometrial stromal sarcoma is a rare form of cancer that occurs due to abnormal and uncontrolled cell growth in the uterus. Endometrial stromal sarcoma, specifically, develops in the supporting connective tissue (stroma) of the uterus. Signs and symptoms of the condition include abnormal uterine bleeding (i.e. bleeding that is not part of menstrual periods or bleeding after menopause); abdominal pain and/or distension; and frequent urination. The exact underlying cause of Endometrial stromal sarcoma is currently unknown. Most cases occur sporadically in people with no family history of the condition.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:213711","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0006745","ORPHANET_ID__c":"ORPHA:213711","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Sarcoma del estroma endometrial","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"sarcoma del estroma endometrial","Spanish_GARD_Synonym__c":"sarcoma estromal de cuerpo de útero","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Endometrial stromal sarcoma is a rare form of cancer that occurs due to abnormal and uncontrolled cell growth in the uterus. Endometrial stromal sarcoma, specifically, develops in the supporting connective tissue (stroma) of the uterus. Signs and symptoms of the condition include abnormal uterine bleeding (i.e. bleeding that is not part of menstrual periods or bleeding after menopause); abdominal pain and/or distension; and frequent urination. The exact underlying cause of Endometrial stromal sarcoma is currently unknown. Most cases occur sporadically in people with no family history of the condition.","Curated_Disease_Description_Source__c":"GARD:0006339","GARD_Synonym__c":"endometrial sarcoma; endometrial stromal sarcoma, high grade; endometrial stromal sarcomas; endometrioid stromal sarcoma; ess; sarcomas, endometrial stromal; stromal sarcoma of the corpus uteri; stromal sarcoma, endometrial; stromal sarcoma, endometrial, malignant; stromal sarcomas, endometrial; undifferentiated endometrial sarcoma","Name":"Endometrial stromal sarcoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Sarcoma UK","Website__c":"https://sarcoma.org.uk/"},{"Account_Name__c":"Foundation for Women's Cancer","Website__c":"https://foundationforwomenscancer.org/"},{"Account_Name__c":"American Cancer Society","Website__c":"https://www.cancer.org"},{"Account_Name__c":"Cancer Hope Network","Website__c":"https://www.cancerhopenetwork.org/"},{"Account_Name__c":"CancerCare","Website__c":"https://www.cancercare.org/"},{"Account_Name__c":"Sarcoma Foundation of America","Website__c":"https://www.curesarcoma.org/"},{"Account_Name__c":"Sarcoma Alliance","Website__c":"https://sarcomaalliance.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Urogenital Disorders","Tag_Category__c":"Disease Category","category_description":"Urinary and reproductive diseases affect the kidneys, ureters, bladder, urethra, or the reproductive organs.","curated_tag_name":"Urinary and reproductive diseases"},{"Tag_Name__c":"Obstetrics / Gynecology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Rare gynecological tumor","Tag_Category__c":"Account;Specialist","curated_tag_name":"Gynecological tumors"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0006339","Source__c":"RareSource"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=60196","Source__c":"C0206630","Xref__c":"MEDGEN:60196"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C8973","Source__c":"C0206630; MONDO:0006745","Xref__c":"C8973"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=699356008","Source__c":"MONDO:0006745","Xref__c":"699356008"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A4226","Source__c":"MONDO:0006745","Xref__c":"DOID:4226"},{"URL__c":"https://www.orpha.net/en/disease/detail/213711","Source__c":"C0206630; MONDO:0006745; ORPHA:213711","Xref__c":"ORPHA:213711"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C018203","Source__c":"C0206630; MONDO:0006745","Xref__c":"D018203"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0206630","Source__c":"C0206630","Xref__c":"C0206630"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=1178986006","Source__c":"C0206630","Xref__c":"1178986006"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0006745","Source__c":"GARD:0006339","Xref__c":"MONDO:0006745"},{"URL__c":"https://secure.ssa.gov/apps10/poms.nsf/lnx/0423022945","Xref__c":"423022945"},{"URL__c":"https://www.ninds.nih.gov/health-information/disorders/empty-sella-syndrome"}],"tags":{"Specialist":["Cancer - Oncologist","Obstetrics / Gynecology","Rare gynecological tumor"],"Disease Category":["Cancer","Urogenital Disorders"],"Account":["Rare gynecological tumor"]},"synonyms":["endometrial sarcoma"," endometrial stromal sarcoma, high grade"," endometrial stromal sarcomas"," endometrioid stromal sarcoma"," ess"," sarcomas, endometrial stromal"," stromal sarcoma of the corpus uteri"," stromal sarcoma, endometrial"," stromal sarcoma, endometrial, malignant"," stromal sarcomas, endometrial"," undifferentiated endometrial sarcoma"]}