{"Name":"Glioma","DiseaseID__c":"GARD:0006513","id":6513,"encodedName":"glioma","IsDeleted":false,"Disease_Name_Full__c":"Glioma","Xref_IDs__c":"115240006; 393564001; C0017638; C3059; D005910; HP:0009733; MEDGEN:9030; MONDO:0021042; ORPHA:182067","USA_Estimate__c":"50,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"80,000 to 800,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0021042","Disease_Description__c":"A benign or malignant brain and spinal cord tumor that arises from glial cells (astrocytes, oligodendrocytes, ependymal cells). Tumors that arise from astrocytes are called astrocytic tumors or astrocytomas. Tumors that arise from oligodendrocytes are called oligodendroglial tumors. Tumors that arise from ependymal cells are called ependymomas.","GARD_Name__c":"Glioma","GARD_Synonym__c":"glial neoplasm; glial tumor; glial tumour; neoplasm of neuroglia; neoplasm of the neuroglia; neuroglial neoplasm; neuroglial tumor; neuroglial tumour; tumor of neuroglia; tumor of the neuroglia; tumour of neuroglia; tumour of the neuroglia","Curated_Disease_Description_Source__c":"GARD:0006513","Curated_Disease_Description__c":"Glial tumors are a type of brain tumor that develop from the glial cells, which are specialized cells that surround and support neurons (nerve cells) in the brain. It is generally classified based on which type of glial cell is involved in the tumor. Astocytomas are tumors that develop from star-shaped glial cells called astrocytes. Ependymomas are tumors that arise from ependymal cells that line the ventricles of the brain and the center of the spinal cord. Oligodendrogliomas are tumors that affect the oligodendrocytes. The symptoms of glial tumors vary by type but may include headaches, nausea and vomiting, confusion, personality changes, trouble with balance, vision problems, speech difficulties, and/or seizures. The exact underlying cause is unknown. In most cases, glial tumors occur sporadically in people with no family history of the condition.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"50,000","Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:182067","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0021042","ORPHANET_ID__c":"ORPHA:182067","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Tumor glial","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"tumor glial","Spanish_GARD_Synonym__c":"glioma","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Glial tumors are a type of brain tumor that develop from the glial cells, which are specialized cells that surround and support neurons (nerve cells) in the brain. It is generally classified based on which type of glial cell is involved in the tumor. Astocytomas are tumors that develop from star-shaped glial cells called astrocytes. Ependymomas are tumors that arise from ependymal cells that line the ventricles of the brain and the center of the spinal cord. Oligodendrogliomas are tumors that affect the oligodendrocytes. The symptoms of glial tumors vary by type but may include headaches, nausea and vomiting, confusion, personality changes, trouble with balance, vision problems, speech difficulties, and/or seizures. The exact underlying cause is unknown. In most cases, glial tumors occur sporadically in people with no family history of the condition.","Curated_Disease_Description_Source__c":"GARD:0006513","GARD_Synonym__c":"glial neoplasm; glial tumor; glial tumour; neoplasm of neuroglia; neoplasm of the neuroglia; neuroglial neoplasm; neuroglial tumor; neuroglial tumour; tumor of neuroglia; tumor of the neuroglia; tumour of neuroglia; tumour of the neuroglia","Name":"Glioma","Curated_USA_Estimate__c":"50,000","estimateUsa":"50,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Pediatric Brain Tumor Foundation","Website__c":"https://www.curethekids.org/"},{"Account_Name__c":"Alex's Lemonade Stand Foundation","Website__c":"https://www.alexslemonade.org/"},{"Account_Name__c":"Brain Foundation","Website__c":"http://www.brainfoundation.org.au/"},{"Account_Name__c":"American Brain Tumor Association","Website__c":"https://www.abta.org/"},{"Account_Name__c":"National Brain Tumor Society","Website__c":"https://braintumor.org/"},{"Account_Name__c":"International Brain Tumour Alliance","Website__c":"https://theibta.org/"},{"Account_Name__c":"Neuro-Oncology Branch Brain Tumor Clinic","Website__c":"https://ccr.cancer.gov/Neuro-Oncology-Branch"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"}],"Diagnosis__c":[{"Type__c":"GTR","Curie__c":"MEDGEN:C0017638"},{"Type__c":"GTR","Curie__c":"MEDGEN:C0349661"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C3059","Source__c":"C0017638; MONDO:0021042","Xref__c":"C3059"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0017638","Source__c":"C0017638","Xref__c":"C0017638"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=393564001","Source__c":"C0017638; MONDO:0021042","Xref__c":"393564001"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C005910","Source__c":"C0017638; MONDO:0021042","Xref__c":"D005910"},{"URL__c":"https://www.orpha.net/en/disease/detail/182067","Source__c":"C0017638; MONDO:0021042; ORPHA:182067","Xref__c":"ORPHA:182067"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=9030","Source__c":"C0017638","Xref__c":"MEDGEN:9030"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=115240006","Source__c":"C0017638","Xref__c":"115240006"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0009733","Source__c":"C0017638","Xref__c":"HP:0009733"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0021042","Source__c":"GARD:0006513","Xref__c":"MONDO:0021042"}],"tags":{"Specialist":["Cancer - Oncologist","Neurology"],"Disease Category":["Cancer","Neurology"]},"synonyms":["glial neoplasm"," glial tumor"," glial tumour"," neoplasm of neuroglia"," neoplasm of the neuroglia"," neuroglial neoplasm"," neuroglial tumor"," neuroglial tumour"," tumor of neuroglia"," tumor of the neuroglia"," tumour of neuroglia"," tumour of the neuroglia"]}