{"Name":"Ichthyosis vulgaris","DiseaseID__c":"GARD:0006752","id":6752,"encodedName":"ichthyosis-vulgaris","IsDeleted":false,"Disease_Name_Full__c":"Ichthyosis vulgaris","Xref_IDs__c":"254157005; C0079584; C84778; D016112; MEDGEN:38217; MONDO:0024304","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0024304","Disease_Description__c":"The most common form of ichthyosis. It is an autosomal dominant inherited or acquired disorder characterized by scaling and desquamation of the skin.","GARD_Name__c":"Ichthyosis vulgaris","GARD_Synonym__c":"dominant ichthyosis vulgaris; ichthyosis simplex","Curated_Disease_Description_Source__c":"GARD:0006752","Curated_Disease_Description__c":"Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin. It often begins in early childhood. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. This condition is inherited in an autosomal dominant pattern.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0024304","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Ichthyosis vulgaris is a common skin disorder passed down through families that leads to dry, scaly skin. It often begins in early childhood. Ichthyosis vulgaris can be a nuisance, but it rarely affects overall health. This condition is inherited in an autosomal dominant pattern.","Curated_Disease_Description_Source__c":"GARD:0006752","GARD_Synonym__c":"dominant ichthyosis vulgaris; ichthyosis simplex","Name":"Ichthyosis vulgaris","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Foundation for Ichthyosis and Related Skin Types","Website__c":"https://www.firstskinfoundation.org/"},{"Account_Name__c":"Ichthyosis Support Group","Website__c":"https://www.ichthyosis.org.uk/"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C016112","Source__c":"C0079584; MONDO:0024304","Xref__c":"D016112"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=38217","Source__c":"C0079584","Xref__c":"MEDGEN:38217"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C84778","Source__c":"C0079584; MONDO:0024304","Xref__c":"C84778"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0079584","Source__c":"C0079584","Xref__c":"C0079584"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=254157005","Source__c":"C0079584","Xref__c":"254157005"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0024304","Source__c":"GARD:0006752","Xref__c":"MONDO:0024304"}],"GARD_Disease_Gene__c":[{"GeneSymbol__c":"FLG","GHR_URL__c":"https://medlineplus.gov/genetics/gene/flg","Gene_Type__c":"protein-coding gene","Causal_Gene__c":true}],"tags":{},"synonyms":["dominant ichthyosis vulgaris"," ichthyosis simplex"]}