{"Name":"Pemphigus and fogo selvagem","DiseaseID__c":"GARD:0007353","id":7353,"encodedName":"pemphigus-and-fogo-selvagem","IsDeleted":false,"Disease_Name_Full__c":"Pemphigus and fogo selvagem","Xref_IDs__c":"46459009; C0263314; C535551; MEDGEN:120470; MONDO:0043257; ORPHA:636955","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MEDGEN:C0263314","Disease_Description__c":null,"GARD_Name__c":"Pemphigus and fogo selvagem","GARD_Synonym__c":"brazilian pemphigus; brazilian pemphigus foliaceus; endemic pemphigus foliaceus; fogo selvagem; south american pemphigus; wildfire pemphigus","Curated_Disease_Description_Source__c":"MEDGEN:C0263314","Curated_Disease_Description__c":"This rare autoimmune skin disease occurs when the body’s immune system attacks the skin and causes blisters just under the outermost layer of skin. These blisters form because of immune proteins called autoantibodies that target a skin protein called desmoglein 1. The disease mainly affects areas of skin that tend to be oily, such as the head, neck, and upper chest and back, and it does not affect the moist linings of the mouth or other mucous membranes. The skin lesions can get worse with exposure to ultraviolet (UV) light and usually become more noticeable over weeks or months. The disease often occurs in children and young adults and is common in rural areas of Brazil and some other parts of South America, as well as North Africa.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0043257","ORPHANET_ID__c":"ORPHA:636955","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Pénfigo foliáceo endémico","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"pénfigo foliáceo endémico","Spanish_GARD_Synonym__c":"fogo selvagem","Category_Linearization__c":"ORPHA:89826","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"This rare autoimmune skin disease occurs when the body’s immune system attacks the skin and causes blisters just under the outermost layer of skin. These blisters form because of immune proteins called autoantibodies that target a skin protein called desmoglein 1. The disease mainly affects areas of skin that tend to be oily, such as the head, neck, and upper chest and back, and it does not affect the moist linings of the mouth or other mucous membranes. The skin lesions can get worse with exposure to ultraviolet (UV) light and usually become more noticeable over weeks or months. The disease often occurs in children and young adults and is common in rural areas of Brazil and some other parts of South America, as well as North Africa.","Curated_Disease_Description_Source__c":"MEDGEN:C0263314","GARD_Synonym__c":"brazilian pemphigus; brazilian pemphigus foliaceus; endemic pemphigus foliaceus; fogo selvagem; south american pemphigus; wildfire pemphigus","Name":"Pemphigus and fogo selvagem","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"International Pemphigus & Pemphigoid Foundation","Website__c":"https://www.pemphigus.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Dermatology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Skin diseases, or integumentary system diseases, affect the skin, hair, nails, sweat glands, or oil glands.","curated_tag_name":"Skin diseases"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:636955"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/636955","Source__c":"MONDO:0043257","Xref__c":"ORPHA:636955"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=46459009","Source__c":"MONDO:0043257","Xref__c":"46459009"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=120470","Source__c":"C0263314","Xref__c":"MEDGEN:120470"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C535551","Source__c":"MONDO:0043257","Xref__c":"C535551"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0263314","Source__c":"C0263314","Xref__c":"C0263314"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0043257","Source__c":"GARD:0007353","Xref__c":"MONDO:0043257"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=1351911000","Source__c":"C0263314","Xref__c":"1351911000"}],"tags":{"Account":["Dermatology"],"Disease Category":["Dermatology"],"Specialist":["Dermatology","Pediatrics"]},"synonyms":["brazilian pemphigus"," brazilian pemphigus foliaceus"," endemic pemphigus foliaceus"," fogo selvagem"," south american pemphigus"," wildfire pemphigus"]}