{"Name":"Mature T-cell and NK-cell non-Hodgkin lymphoma","DiseaseID__c":"GARD:0007368","id":7368,"encodedName":"mature-t-cell-and-nk-cell-non-hodgkin-lymphoma","IsDeleted":false,"Disease_Name_Full__c":"Mature T-cell and NK-cell non-Hodgkin lymphoma","Xref_IDs__c":"109977009; C3468; C5551485; C84.4; D016411; DOID:0050743; DOID:0050749; MEDGEN:1790498; MONDO:0000430","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0000430","Disease_Description__c":"This type of lymphoma is not frequently seen in the western hemisphere. Clinically, with the exception of anaplastic large cell lymphoma, mature T- and NK-cell lymphomas are among the most aggressive of all hematopoietic neoplasms. Representative disease entities include mycosis fungoides, angioimmunoblastic T-cell lymphoma, hepatosplenic T-cell lymphoma, and anaplastic large cell lymphoma.","GARD_Name__c":"Mature T-cell and NK-cell non-Hodgkin lymphoma","GARD_Synonym__c":"mature t-and nk-cell lymphoma; mature t-cell and nk-cell lymphoma; mature t-cell and nk-cell non-hodgkin's lymphoma; mature t-cell lymphoma; mature t-cell non-hodgkin's lymphoma; ptcl","Curated_Disease_Description_Source__c":"MEDGEN:C0079774","Curated_Disease_Description__c":"A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0000430","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A group of malignant lymphomas thought to derive from peripheral T-lymphocytes in lymph nodes and other nonlymphoid sites. They include a broad spectrum of lymphocyte morphology, but in all instances express T-cell markers admixed with epithelioid histiocytes, plasma cells, and eosinophils. Although markedly similar to large-cell immunoblastic lymphoma (LYMPHOMA, LARGE-CELL, IMMUNOBLASTIC), this group's unique features warrant separate treatment.","Curated_Disease_Description_Source__c":"MEDGEN:C0079774","GARD_Synonym__c":"mature t-and nk-cell lymphoma; mature t-cell and nk-cell lymphoma; mature t-cell and nk-cell non-hodgkin's lymphoma; mature t-cell lymphoma; mature t-cell non-hodgkin's lymphoma; ptcl","Name":"Mature T-cell and NK-cell non-Hodgkin lymphoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Lymphoma Research Foundation","Website__c":"https://lymphoma.org/"},{"Account_Name__c":"HealthTree Foundation","Website__c":"https://healthtree.org/"},{"Account_Name__c":"Lymphoma Coalition","Website__c":"https://lymphomacoalition.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/C84.4","Source__c":"MONDO:0000430","Xref__c":"C84.4"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A0050749","Source__c":"MONDO:0000430","Xref__c":"DOID:0050749"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=109977009","Source__c":"MONDO:0000430","Xref__c":"109977009"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A0050743","Source__c":"MONDO:0000430","Xref__c":"DOID:0050743"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C016411","Source__c":"MONDO:0000430","Xref__c":"D016411"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5551485","Source__c":"C5551485","Xref__c":"C5551485"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C3468","Source__c":"C5551485; MONDO:0000430","Xref__c":"C3468"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1790498","Source__c":"C5551485","Xref__c":"MEDGEN:1790498"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0000430","Source__c":"GARD:0007368","Xref__c":"MONDO:0000430"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["mature t-and nk-cell lymphoma"," mature t-cell and nk-cell lymphoma"," mature t-cell and nk-cell non-hodgkin's lymphoma"," mature t-cell lymphoma"," mature t-cell non-hodgkin's lymphoma"," ptcl"]}