{"Name":"Reye syndrome","DiseaseID__c":"GARD:0007570","id":7570,"encodedName":"reye-syndrome","IsDeleted":false,"Disease_Name_Full__c":"Reye syndrome","Xref_IDs__c":"74351001; C0035400; C34983; D012202; DOID:14525; G93.7; MEDGEN:19772; MONDO:0005942; ORPHA:3096","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":2,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":2,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":4,"Description_Source__c":"MONDO:0005942","Disease_Description__c":"An acute and potentially fatal metabolic disorder characterized by cerebral edema, fatty liver and hypoglycemia. It occurs primarily in children and has been associated with the use of aspirin for the treatment of viral infections. However, it can also occur in the absence of aspirin use.","GARD_Name__c":"Reye syndrome","GARD_Synonym__c":"fatty liver with encephalopathy; reye's encephalopathy; reye's syndrome","Curated_Disease_Description_Source__c":"MONDO:0005942","Curated_Disease_Description__c":"An acute and potentially fatal metabolic disorder characterized by cerebral edema, fatty liver and hypoglycemia. It occurs primarily in children and has been associated with the use of aspirin for the treatment of viral infections. However, it can also occur in the absence of aspirin use.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at a variety of ages","SourceID__c":"ORPHA:3096","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0005942","ORPHANET_ID__c":"ORPHA:3096","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Síndrome de reye","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"síndrome de reye","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:98006","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"An acute and potentially fatal metabolic disorder characterized by cerebral edema, fatty liver and hypoglycemia. It occurs primarily in children and has been associated with the use of aspirin for the treatment of viral infections. However, it can also occur in the absence of aspirin use.","Curated_Disease_Description_Source__c":"MONDO:0005942","GARD_Synonym__c":"fatty liver with encephalopathy; reye's encephalopathy; reye's syndrome","Name":"Reye syndrome","estimateUsa":""}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Rheumatology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adolescent","Provided_By__c":"ORPHA:3096"},{"Age_At_Onset__c":"Infancy","Provided_By__c":"ORPHA:3096"},{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:3096"},{"Age_At_Onset__c":"Childhood","Provided_By__c":"ORPHA:3096"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C012202","Source__c":"C0035400; MONDO:0005942","Xref__c":"D012202"},{"URL__c":"https://www.orpha.net/en/disease/detail/3096","Source__c":"C0035400; MONDO:0005942; ORPHA:3096","Xref__c":"ORPHA:3096"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=19772","Source__c":"C0035400","Xref__c":"MEDGEN:19772"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A14525","Source__c":"MONDO:0005942","Xref__c":"DOID:14525"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0035400","Source__c":"C0035400","Xref__c":"C0035400"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=74351001","Source__c":"C0035400; MONDO:0005942","Xref__c":"74351001"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C34983","Source__c":"C0035400; MONDO:0005942","Xref__c":"C34983"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/G93.7","Source__c":"MONDO:0005942","Xref__c":"G93.7"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0005942","Source__c":"GARD:0007570","Xref__c":"MONDO:0005942"},{"URL__c":"https://medlineplus.gov/reyesyndrome.html"},{"URL__c":"https://www.ninds.nih.gov/health-information/disorders/reyes-syndrome"}],"tags":{"Specialist":["Rheumatology","Pediatrics"]},"synonyms":["fatty liver with encephalopathy"," reye's encephalopathy"," reye's syndrome"]}