{"Name":"Kidney Wilms tumor","DiseaseID__c":"GARD:0007892","id":7892,"encodedName":"kidney-wilms-tumor","IsDeleted":false,"Disease_Name_Full__c":"Kidney Wilms tumor","Xref_IDs__c":"302849000; C40407; CN305775; DOID:2154; DOID:5176; MEDGEN:989515; MONDO:0019004","USA_Estimate__c":"5,000","No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":2,"World_Estimate__c":"8,000 to 80,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":2,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":5,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0019004","Disease_Description__c":"An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver.","GARD_Name__c":"Kidney Wilms tumor","GARD_Synonym__c":"nephroblastoma, malignant; renal embryonic tumor; renal embryonic tumour; renal wilms tumor; renal wilms tumour; renal wilms' tumor; renal wilms' tumour; wilms tumor of the kidney; wilms tumour of the kidney; wilms' tumor of the kidney; wilms' tumour of the kidney","Curated_Disease_Description_Source__c":"MONDO:0019004","Curated_Disease_Description__c":"An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"5,000","Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:654","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0019004","ORPHANET_ID__c":"ORPHA:654","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"An embryonal pediatric tumor of the kidney which may also be seen rarely in adults. The peak incidence of Wilms tumor is between the second and fifth year of life. Microscopically, it is composed of a mixture of cellular elements (blastemal, stromal, and epithelial). The most common sites of metastasis include the regional lymph nodes, lungs, and liver.","Curated_Disease_Description_Source__c":"MONDO:0019004","GARD_Synonym__c":"nephroblastoma, malignant; renal embryonic tumor; renal embryonic tumour; renal wilms tumor; renal wilms tumour; renal wilms' tumor; renal wilms' tumour; wilms tumor of the kidney; wilms tumour of the kidney; wilms' tumor of the kidney; wilms' tumour of the kidney","Name":"Kidney Wilms tumor","Curated_USA_Estimate__c":"5,000","estimateUsa":"5,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Alex's Lemonade Stand Foundation","Website__c":"https://www.alexslemonade.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Genetics","Tag_Category__c":"Cause;Disease Category;Specialist","category_description":"Genetic diseases affect the DNA, or genetic instructions, which directs how tissues, organs, and body systems function.","curated_tag_name":"Genetic diseases"},{"Tag_Name__c":"Nephrology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Kidney diseases affect the kidneys' ability to remove waste and water from blood, create urine, or make certain hormones.","curated_tag_name":"Kidney diseases"}],"Diagnosis__c":[{"Type__c":"GTR","Curie__c":"MEDGEN:C0027708"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0007892","Source__c":"RareSource"},{"URL__c":"https://www.ncbi.nlm.nih.gov/books/NBK1360","Source__c":"Gene Review","Xref__c":"NBK1360"},{"URL__c":"https://www.ncbi.nlm.nih.gov/books/NBK1294","Source__c":"Gene Review","Xref__c":"NBK1294"},{"URL__c":"https://www.ncbi.nlm.nih.gov/books/NBK556455","Source__c":"Gene Review","Xref__c":"NBK556455"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C40407","Source__c":"MONDO:0019004","Xref__c":"C40407"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=302849000","Source__c":"MONDO:0019004","Xref__c":"302849000"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A5176","Source__c":"MONDO:0019004","Xref__c":"DOID:5176"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A2154","Source__c":"MONDO:0019004","Xref__c":"DOID:2154"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019004","Source__c":"GARD:0007892","Xref__c":"MONDO:0019004"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=989515","Source__c":"CN305775","Xref__c":"MEDGEN:989515"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/CN305775","Source__c":"CN305775","Xref__c":"CN305775"},{"URL__c":"https://medlineplus.gov/genetics/condition/wilms-tumor"},{"URL__c":"https://medlineplus.gov/wilmstumor.html"}],"tags":{"Specialist":["Cancer - Oncologist","Genetics","Nephrology"],"Disease Category":["Cancer","Genetics","Nephrology"],"Cause":["Genetics"],"Account":["Nephrology"]},"synonyms":["nephroblastoma, malignant"," renal embryonic tumor"," renal embryonic tumour"," renal wilms tumor"," renal wilms tumour"," renal wilms' tumor"," renal wilms' tumour"," wilms tumor of the kidney"," wilms tumour of the kidney"," wilms' tumor of the kidney"," wilms' tumour of the kidney"]}