{"Name":"Large-cell immunoblastic lymphoma","DiseaseID__c":"GARD:0008219","id":8219,"encodedName":"large-cell-immunoblastic-lymphoma","IsDeleted":false,"Disease_Name_Full__c":"Large-cell immunoblastic lymphoma","Xref_IDs__c":"C0079746; C3461; D016400; MEDGEN:86955; MONDO:0022037","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0022037","Disease_Description__c":"Malignant lymphoma characterized by the presence of immunoblasts with uniformly round-to-oval nuclei, one or more prominent nucleoli, and abundant cytoplasm. This class may be subdivided into plasmacytoid and clear-cell types based on cytoplasmic characteristics. A third category, pleomorphous, may be analogous to some of the peripheral T-cell lymphomas (LYMPHOMA, T-CELL, PERIPHERAL) recorded in both the United States and Japan.","GARD_Name__c":"Large-cell immunoblastic lymphoma","GARD_Synonym__c":"diffuse non-hodgkin lymphoma, immunoblastic; diffuse non-hodgkin's immunoblastic (diffuse) lymphoma; diffuse non-hodgkin's lymphoma, immunoblastic; diffuse non-hodgkin's lymphoma, immunoblastic (clinical); immunoblastic malignant lymphoma - large cell; lymphoma, immunoblastic, high grade; malignant lymphoma - immunoblastic","Curated_Disease_Description_Source__c":"MEDGEN:C0079746","Curated_Disease_Description__c":"A diffuse large B-cell lymphoma characterized by the presence of immunoblasts with uniformly round-to-oval nuclei, a prominent nucleolus, and abundant cytoplasm.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0022037","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A diffuse large B-cell lymphoma characterized by the presence of immunoblasts with uniformly round-to-oval nuclei, a prominent nucleolus, and abundant cytoplasm.","Curated_Disease_Description_Source__c":"MEDGEN:C0079746","GARD_Synonym__c":"diffuse non-hodgkin lymphoma, immunoblastic; diffuse non-hodgkin's immunoblastic (diffuse) lymphoma; diffuse non-hodgkin's lymphoma, immunoblastic; diffuse non-hodgkin's lymphoma, immunoblastic (clinical); immunoblastic malignant lymphoma - large cell; lymphoma, immunoblastic, high grade; malignant lymphoma - immunoblastic","Name":"Large-cell immunoblastic lymphoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"The Leukemia & Lymphoma Society","Website__c":"www.lls.org"},{"Account_Name__c":"Lymphoma Research Foundation","Website__c":"https://lymphoma.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=86955","Source__c":"C0079746","Xref__c":"MEDGEN:86955"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C016400","Source__c":"C0079746; MONDO:0022037","Xref__c":"D016400"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0079746","Source__c":"C0079746","Xref__c":"C0079746"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C3461","Source__c":"C0079746","Xref__c":"C3461"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=109966003","Source__c":"C0079746","Xref__c":"109966003"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0022037","Source__c":"GARD:0008219","Xref__c":"MONDO:0022037"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["diffuse non-hodgkin lymphoma, immunoblastic"," diffuse non-hodgkin's immunoblastic (diffuse) lymphoma"," diffuse non-hodgkin's lymphoma, immunoblastic"," diffuse non-hodgkin's lymphoma, immunoblastic (clinical)"," immunoblastic malignant lymphoma - large cell"," lymphoma, immunoblastic, high grade"," malignant lymphoma - immunoblastic"]}