{"Name":"B-cell prolymphocytic leukemia","DiseaseID__c":"GARD:0008223","id":8223,"encodedName":"b-cell-prolymphocytic-leukemia","IsDeleted":false,"Disease_Name_Full__c":"B-cell prolymphocytic leukemia","Xref_IDs__c":"277619001; C0475801; C4753; D054403; DOID:0081041; MEDGEN:105396; MONDO:0019461; ORPHA:86852","USA_Estimate__c":"1,000","No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"1 to 8,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0019461","Disease_Description__c":"A neoplasm of prolymphocytes affecting the blood, bone marrow, and spleen. It is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.","GARD_Name__c":"B-cell prolymphocytic leukemia","GARD_Synonym__c":"b prolymphocytic leukaemia; b prolymphocytic leukemia; b-pll; prolymphocytic leukemia of b-cell type; prolymphocytic leukemia, b-cell type","Curated_Disease_Description_Source__c":"MONDO:0019461","Curated_Disease_Description__c":"A neoplasm of prolymphocytes affecting the blood, bone marrow, and spleen. It is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"1,000","Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:86852","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0019461","ORPHANET_ID__c":"ORPHA:86852","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Leucemia prolinfocítica de células b","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"leucemia prolinfocítica de células b","Spanish_GARD_Synonym__c":"b-pll","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A neoplasm of prolymphocytes affecting the blood, bone marrow, and spleen. It is characterized by prolymphocytes exceeding 55% of the lymphoid cells in the blood and profound splenomegaly.","Curated_Disease_Description_Source__c":"MONDO:0019461","GARD_Synonym__c":"b prolymphocytic leukaemia; b prolymphocytic leukemia; b-pll; prolymphocytic leukemia of b-cell type; prolymphocytic leukemia, b-cell type","Name":"B-cell prolymphocytic leukemia","Curated_USA_Estimate__c":"1,000","estimateUsa":"1,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"HealthTree Foundation","Website__c":"https://healthtree.org/"},{"Account_Name__c":"Blood Cancer United","Website__c":"https://bloodcancerunited.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Hematology","Tag_Category__c":"Disease Category;Specialist","category_description":"Blood diseases affect the blood or blood-forming organs, including red blood cells, white blood cells, platelets, plasma, and bone marrow.","curated_tag_name":"Blood diseases"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:86852"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0475801","Source__c":"C0475801","Xref__c":"C0475801"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=277619001","Source__c":"C0475801; MONDO:0019461","Xref__c":"277619001"},{"URL__c":"https://www.orpha.net/en/disease/detail/86852","Source__c":"C0475801; MONDO:0019461; ORPHA:86852","Xref__c":"ORPHA:86852"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=105396","Source__c":"C0475801","Xref__c":"MEDGEN:105396"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C4753","Source__c":"C0475801; MONDO:0019461","Xref__c":"C4753"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A0081041","Source__c":"MONDO:0019461","Xref__c":"DOID:0081041"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C054403","Source__c":"C0475801; MONDO:0019461","Xref__c":"D054403"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=128820007","Source__c":"C0475801","Xref__c":"128820007"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019461","Source__c":"GARD:0008223","Xref__c":"MONDO:0019461"}],"tags":{"Specialist":["Cancer - Oncologist","Hematology"],"Disease Category":["Cancer","Hematology"]},"synonyms":["b prolymphocytic leukaemia"," b prolymphocytic leukemia"," b-pll"," prolymphocytic leukemia of b-cell type"," prolymphocytic leukemia, b-cell type"]}