{"Name":"Non-Langerhans cell histiocytosis","DiseaseID__c":"GARD:0008231","id":8231,"encodedName":"non-langerhans-cell-histiocytosis","IsDeleted":false,"Disease_Name_Full__c":"Non-Langerhans cell histiocytosis","Xref_IDs__c":"127069007; C0019624; D015616; DOID:4330; MEDGEN:9265; MONDO:0015531; ORPHA:157987","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0015531","Disease_Description__c":"Group of disorders which feature accumulations of active HISTIOCYTES and LYMPHOCYTES, but where the histiocytes are not LANGERHANS CELLS. The group includes HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; SINUS HISTIOCYTOSIS; xanthogranuloma; reticulohistiocytoma; juvenile XANTHOGRANULOMA; xanthoma disseminatum; as well as the lipid storage diseases (SEA-BLUE HISTIOCYTE SYNDROME; and NIEMANN-PICK DISEASES).","GARD_Name__c":"Non-Langerhans cell histiocytosis","GARD_Synonym__c":"non-langerhans-cell histiocytosis","Curated_Disease_Description_Source__c":"MONDO:0015531","Curated_Disease_Description__c":"Group of disorders which feature accumulations of active HISTIOCYTES and LYMPHOCYTES, but where the histiocytes are not LANGERHANS CELLS. The group includes HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; SINUS HISTIOCYTOSIS; xanthogranuloma; reticulohistiocytoma; juvenile XANTHOGRANULOMA; xanthoma disseminatum; as well as the lipid storage diseases (SEA-BLUE HISTIOCYTE SYNDROME; and NIEMANN-PICK DISEASES).","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:157987","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0015531","ORPHANET_ID__c":"ORPHA:157987","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Histiocitosis de células no langerhans","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"histiocitosis de células no langerhans","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:98023","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Group of disorders which feature accumulations of active HISTIOCYTES and LYMPHOCYTES, but where the histiocytes are not LANGERHANS CELLS. The group includes HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS; SINUS HISTIOCYTOSIS; xanthogranuloma; reticulohistiocytoma; juvenile XANTHOGRANULOMA; xanthoma disseminatum; as well as the lipid storage diseases (SEA-BLUE HISTIOCYTE SYNDROME; and NIEMANN-PICK DISEASES).","Curated_Disease_Description_Source__c":"MONDO:0015531","GARD_Synonym__c":"non-langerhans-cell histiocytosis","Name":"Non-Langerhans cell histiocytosis","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Histiocytosis Association","Website__c":"https://www.histio.org/"},{"Account_Name__c":"Histiocytosis Association of Canada","Website__c":"https://histiocytosis.ca/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Rheumatology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Dermatology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Skin diseases, or integumentary system diseases, affect the skin, hair, nails, sweat glands, or oil glands.","curated_tag_name":"Skin diseases"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0019624","Source__c":"C0019624","Xref__c":"C0019624"},{"URL__c":"https://www.orpha.net/en/disease/detail/157987","Source__c":"C0019624; MONDO:0015531; ORPHA:157987","Xref__c":"ORPHA:157987"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C015616","Source__c":"C0019624; MONDO:0015531","Xref__c":"D015616"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=9265","Source__c":"C0019624","Xref__c":"MEDGEN:9265"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A4330","Source__c":"MONDO:0015531","Xref__c":"DOID:4330"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=127069007","Source__c":"MONDO:0015531","Xref__c":"127069007"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0015531","Source__c":"GARD:0008231","Xref__c":"MONDO:0015531"}],"tags":{"Specialist":["Rheumatology","Dermatology"],"Account":["Dermatology"],"Disease Category":["Dermatology"]},"synonyms":["non-langerhans-cell histiocytosis"]}