{"Name":"Dementia associated with AIDS","DiseaseID__c":"GARD:0008250","id":8250,"encodedName":"dementia-associated-with-aids","IsDeleted":false,"Disease_Name_Full__c":"Dementia associated with AIDS","Xref_IDs__c":"421529006; C0001849; C2864; D015526; MEDGEN:177; MONDO:0020689","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":1,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0020689","Disease_Description__c":"A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)","GARD_Name__c":"Dementia associated with AIDS","GARD_Synonym__c":"acquired immune deficiency syndrome dementia complex; acquired immune deficiency syndrome-related dementia; adc - acquired immune deficiency syndrome dementia complex; aids (acquired immunodeficiency syndrome) dementia complex; aids dementia; aids dementia complex; dementia with acquired immunodeficiency syndrome; dementia with aids (acquired immunodeficiency syndrome)","Curated_Disease_Description_Source__c":"MONDO:0020689","Curated_Disease_Description__c":"A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0020689","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)","Curated_Disease_Description_Source__c":"MONDO:0020689","GARD_Synonym__c":"acquired immune deficiency syndrome dementia complex; acquired immune deficiency syndrome-related dementia; adc - acquired immune deficiency syndrome dementia complex; aids (acquired immunodeficiency syndrome) dementia complex; aids dementia; aids dementia complex; dementia with acquired immunodeficiency syndrome; dementia with aids (acquired immunodeficiency syndrome)","Name":"Dementia associated with AIDS","estimateUsa":""}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=421529006","Source__c":"C0001849; MONDO:0020689","Xref__c":"421529006"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C2864","Source__c":"C0001849; MONDO:0020689","Xref__c":"C2864"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C015526","Source__c":"C0001849; MONDO:0020689","Xref__c":"D015526"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=177","Source__c":"C0001849","Xref__c":"MEDGEN:177"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0001849","Source__c":"C0001849","Xref__c":"C0001849"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0020689","Source__c":"GARD:0008250","Xref__c":"MONDO:0020689"}],"tags":{},"synonyms":["acquired immune deficiency syndrome dementia complex"," acquired immune deficiency syndrome-related dementia"," adc - acquired immune deficiency syndrome dementia complex"," aids (acquired immunodeficiency syndrome) dementia complex"," aids dementia"," aids dementia complex"," dementia with acquired immunodeficiency syndrome"," dementia with aids (acquired immunodeficiency syndrome)"]}