{"Name":"Panuveitis","DiseaseID__c":"GARD:0008577","id":8577,"encodedName":"panuveitis","IsDeleted":false,"Disease_Name_Full__c":"Panuveitis","Xref_IDs__c":"75614007; C0030343; C84989; D015864; DOID:12030; H44.11; HP:0012121; MEDGEN:45303; MONDO:0017255; ORPHA:280898","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0017255","Disease_Description__c":"A disorder characterized by inflammation of the entire uvea which includes the iris, ciliary body, and choroid. Causes include systemic infections, sarcoidosis, and cancers.","GARD_Name__c":"Panuveitis","GARD_Synonym__c":"diffuse uveitis; inflammation of the whole uveal tract; panuveitis (disease); total uveitis","Curated_Disease_Description_Source__c":"GARD:0008577","Curated_Disease_Description__c":"Panuveitis is inflammation of all layers of the uvea of the eye, which includes the iris, ciliary body, and choroid. These make up the middle layer of the eye. The condition can also affect the lens, retina, optic nerve, and vitreous, causing reduced vision or blindness. Signs and symptoms may include eye redness and pain; blurring; light sensitivity; decreased vision; and seeing floaters. In many cases the specific cause is unknown, but in some cases it occurs in association with other eye conditions, or with another condition or infection that also affects other body parts.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:280898","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0017255","ORPHANET_ID__c":"ORPHA:280898","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Panuveítis","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"panuveítis","Spanish_GARD_Synonym__c":"uveítis total","Category_Linearization__c":"ORPHA:97966","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Panuveitis is inflammation of all layers of the uvea of the eye, which includes the iris, ciliary body, and choroid. These make up the middle layer of the eye. The condition can also affect the lens, retina, optic nerve, and vitreous, causing reduced vision or blindness. Signs and symptoms may include eye redness and pain; blurring; light sensitivity; decreased vision; and seeing floaters. In many cases the specific cause is unknown, but in some cases it occurs in association with other eye conditions, or with another condition or infection that also affects other body parts.","Curated_Disease_Description_Source__c":"GARD:0008577","GARD_Synonym__c":"diffuse uveitis; inflammation of the whole uveal tract; panuveitis (disease); total uveitis","Name":"Panuveitis","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Ocular Immunology and Uveitis Foundation","Website__c":"https://uveitis.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Ophthalmology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:280898"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C84989","Source__c":"C0030343; MONDO:0017255","Xref__c":"C84989"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0030343","Source__c":"C0030343","Xref__c":"C0030343"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C015864","Source__c":"C0030343; MONDO:0017255","Xref__c":"D015864"},{"URL__c":"https://www.orpha.net/en/disease/detail/280898","Source__c":"C0030343; MONDO:0017255; ORPHA:280898","Xref__c":"ORPHA:280898"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=45303","Source__c":"C0030343","Xref__c":"MEDGEN:45303"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=75614007","Source__c":"C0030343; MONDO:0017255","Xref__c":"75614007"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A12030","Source__c":"MONDO:0017255","Xref__c":"DOID:12030"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0017255","Source__c":"GARD:0008577","Xref__c":"MONDO:0017255"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/H44.11","Source__c":"MONDO:0017255","Xref__c":"H44.11"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0012121","Source__c":"C0030343","Xref__c":"HP:0012121"}],"tags":{"Specialist":["Ophthalmology","Pediatrics"]},"synonyms":["diffuse uveitis"," inflammation of the whole uveal tract"," panuveitis (disease)"," total uveitis"]}