{"Name":"Lipoid nephrosis","DiseaseID__c":"GARD:0009147","id":9147,"encodedName":"lipoid-nephrosis","IsDeleted":false,"Disease_Name_Full__c":"Lipoid nephrosis","Xref_IDs__c":"44785005; C0027721; C34844; D009402; DOID:10966; MEDGEN:10307; MONDO:0006835","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0006835","Disease_Description__c":"A glomerular disorder characterized by the electron microscopic finding of loss of podocyte foot processes. Light microscopic examination does not show glomerular changes. Patients present with proteinuria and nephrotic syndrome.","GARD_Name__c":"Lipoid nephrosis","GARD_Synonym__c":"light negative glomerulonephritis; lipid nephrosis; mcd - minimal change disease; mcgn - minimal change glomerulonephritis; mcn - minimal change nephropathy; minimal change disease; minimal change glomerulonephritis; minimal change nephropathy; nil disease","Curated_Disease_Description_Source__c":"GARD:0009147","Curated_Disease_Description__c":"Minimal change disease is a kidney disease in which there is damage to the filtering units of the kidney (glomeruli). It is the most common cause of nephrotic syndrome in children. Nephrotic syndrome is comprised of a group of symptoms including protein in the urine (proteinuria), low protein levels in the blood, high cholesterol and triglycerides, an increased risk for blood clots, and swelling. Other symptoms of this disease include weight gain and a foamy appearance of the urine. The cause of Minimal change disease is unknown, but it may occur following an allergic reaction or infection.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0006835","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Minimal change disease is a kidney disease in which there is damage to the filtering units of the kidney (glomeruli). It is the most common cause of nephrotic syndrome in children. Nephrotic syndrome is comprised of a group of symptoms including protein in the urine (proteinuria), low protein levels in the blood, high cholesterol and triglycerides, an increased risk for blood clots, and swelling. Other symptoms of this disease include weight gain and a foamy appearance of the urine. The cause of Minimal change disease is unknown, but it may occur following an allergic reaction or infection.","Curated_Disease_Description_Source__c":"GARD:0009147","GARD_Synonym__c":"light negative glomerulonephritis; lipid nephrosis; mcd - minimal change disease; mcgn - minimal change glomerulonephritis; mcn - minimal change nephropathy; minimal change disease; minimal change glomerulonephritis; minimal change nephropathy; nil disease","Name":"Lipoid nephrosis","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Halpin Foundation","Website__c":"http://www.halpinfoundation.org/index.html"},{"Account_Name__c":"National Kidney Foundation","Website__c":"https://www.kidney.org/"},{"Account_Name__c":"NephCure Kidney International","Website__c":"https://nephcure.org/"}],"External_Identifier_Disease__c":[{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0027721","Source__c":"C0027721","Xref__c":"C0027721"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=44785005","Source__c":"C0027721; MONDO:0006835","Xref__c":"44785005"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C34844","Source__c":"C0027721; MONDO:0006835","Xref__c":"C34844"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=10307","Source__c":"C0027721","Xref__c":"MEDGEN:10307"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C009402","Source__c":"C0027721; MONDO:0006835","Xref__c":"D009402"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A10966","Source__c":"MONDO:0006835","Xref__c":"DOID:10966"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0006835","Source__c":"GARD:0009147","Xref__c":"MONDO:0006835"},{"URL__c":"https://hpo.jax.org/browse/term/HP:0012579","Source__c":"C0027721","Xref__c":"HP:0012579"}],"tags":{},"synonyms":["light negative glomerulonephritis"," lipid nephrosis"," mcd - minimal change disease"," mcgn - minimal change glomerulonephritis"," mcn - minimal change nephropathy"," minimal change disease"," minimal change glomerulonephritis"," minimal change nephropathy"," nil disease"]}