{"Name":"Childhood brain stem glioma","DiseaseID__c":"GARD:0009306","id":9306,"encodedName":"childhood-brain-stem-glioma","IsDeleted":false,"Disease_Name_Full__c":"Childhood brain stem glioma","Xref_IDs__c":"C0278600; C9042; DOID:6383; MEDGEN:124481; MONDO:0003869","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0003869","Disease_Description__c":"An abnormal growth of the cells that comprise the tissues of the brainstem. While the tumor may be histologically benign, it can produce great morbidity due to its location. It presents most commonly in the first two decades of life.","GARD_Name__c":"Childhood brain stem glioma","GARD_Synonym__c":"brain stem glioma of childhood; childhood brainstem glioma; childhood glioma of brain stem; childhood glioma of brainstem; childhood glioma of the brain stem; childhood glioma of the brainstem; paediatric brain stem glioma; paediatric brainstem glioma; paediatric glioma of brain stem; paediatric glioma of brainstem; paediatric glioma of the brain stem; paediatric glioma of the brainstem; pediatric brain stem glioma; pediatric brainstem glioma; pediatric glioma of brain stem; pediatric glioma of brainstem; pediatric glioma of the brain stem; pediatric glioma of the brainstem","Curated_Disease_Description_Source__c":"GARD:0009306","Curated_Disease_Description__c":"Childhood brain stem glioma is a rare condition in which abnormal cells develop in the tissues of the brain stem (the part of the brain connected to the spinal cord). The condition can be benign (noncancerous) or malignant (cancerous). The severity of the condition and the associated symptoms vary based on the size and location of the tumor and how quickly the tumor is growing. Common features include difficulty walking; loss of the ability to move one side of the body or face; vision or hearing problems; headaches (particularly in the morning); nausea and vomiting; unusual sleepiness; and behavioral changes. In most cases, the underlying cause of Childhood brain stem glioma is unknown. Certain genetic conditions, such as neurofibromatosis type I, are associated with an increased risk of childhood brainstem glioma.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0003869","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Childhood brain stem glioma is a rare condition in which abnormal cells develop in the tissues of the brain stem (the part of the brain connected to the spinal cord). The condition can be benign (noncancerous) or malignant (cancerous). The severity of the condition and the associated symptoms vary based on the size and location of the tumor and how quickly the tumor is growing. Common features include difficulty walking; loss of the ability to move one side of the body or face; vision or hearing problems; headaches (particularly in the morning); nausea and vomiting; unusual sleepiness; and behavioral changes. In most cases, the underlying cause of Childhood brain stem glioma is unknown. Certain genetic conditions, such as neurofibromatosis type I, are associated with an increased risk of childhood brainstem glioma.","Curated_Disease_Description_Source__c":"GARD:0009306","GARD_Synonym__c":"brain stem glioma of childhood; childhood brainstem glioma; childhood glioma of brain stem; childhood glioma of brainstem; childhood glioma of the brain stem; childhood glioma of the brainstem; paediatric brain stem glioma; paediatric brainstem glioma; paediatric glioma of brain stem; paediatric glioma of brainstem; paediatric glioma of the brain stem; paediatric glioma of the brainstem; pediatric brain stem glioma; pediatric brainstem glioma; pediatric glioma of brain stem; pediatric glioma of brainstem; pediatric glioma of the brain stem; pediatric glioma of the brainstem","Name":"Childhood brain stem glioma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"A Kids’ Brain Tumor Cure Foundation","Website__c":"https://akidsbraintumorcure.org/"},{"Account_Name__c":"Alex's Lemonade Stand Foundation","Website__c":"https://www.alexslemonade.org/"},{"Account_Name__c":"Pediatric Brain Tumor Foundation","Website__c":"https://www.curethekids.org/"},{"Account_Name__c":"American Brain Tumor Association","Website__c":"https://www.abta.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=124481","Source__c":"C0278600","Xref__c":"MEDGEN:124481"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0278600","Source__c":"C0278600","Xref__c":"C0278600"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C9042","Source__c":"C0278600; MONDO:0003869","Xref__c":"C9042"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A6383","Source__c":"MONDO:0003869","Xref__c":"DOID:6383"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0003869","Source__c":"GARD:0009306","Xref__c":"MONDO:0003869"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["brain stem glioma of childhood"," childhood brainstem glioma"," childhood glioma of brain stem"," childhood glioma of brainstem"," childhood glioma of the brain stem"," childhood glioma of the brainstem"," paediatric brain stem glioma"," paediatric brainstem glioma"," paediatric glioma of brain stem"," paediatric glioma of brainstem"," paediatric glioma of the brain stem"," paediatric glioma of the brainstem"," pediatric brain stem glioma"," pediatric brainstem glioma"," pediatric glioma of brain stem"," pediatric glioma of brainstem"," pediatric glioma of the brain stem"," pediatric glioma of the brainstem"]}