{"Name":"Renal pelvis/ureter urothelial carcinoma","DiseaseID__c":"GARD:0009376","id":9376,"encodedName":"renal-pelvisureter-urothelial-carcinoma","IsDeleted":false,"Disease_Name_Full__c":"Renal pelvis/ureter urothelial carcinoma","Xref_IDs__c":"C7716; MONDO:0020654; ORPHA:598216","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":2,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":2,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":3,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0020654","Disease_Description__c":"A transitional cell carcinoma that arises from the renal pelvis and ureter.","GARD_Name__c":"Renal pelvis/ureter urothelial carcinoma","GARD_Synonym__c":"renal pelvis and ureter tcc; renal pelvis and ureter transitional cell cancer; renal pelvis and ureter transitional cell carcinoma; renal pelvis and ureter urothelial carcinoma; tcc of renal pelvis and ureter; tcc of the renal pelvis and ureter; transitional cell cancer of renal pelvis and ureter; transitional cell cancer of the renal pelvis and ureter; transitional cell carcinoma of renal pelvis and ureter; transitional cell carcinoma of the pelvis and ureter; transitional cell carcinoma of the upper urinary tract; upper tract urothelial carcinoma; urothelial carcinoma of the renal pelvis and ureter; utuc","Curated_Disease_Description_Source__c":"ORPHA:598216","Curated_Disease_Description__c":"A rare urinary tract tumor characterized by a malignant neoplasm arising from urothelial cells of the pyelocaliceal cavities and ureter. The tumor may be multifocal and bilateral in some cases and is more common in males than in females. Cigarette smoking and occupational exposure are major risk factors. Patients most commonly present with visible or non-visible hematuria and/or flank pain due to obstruction of the flow of urine by tumor tissue, or (less often) to local tumor growth. Systemic symptoms such as anorexia, weight loss, malaise, fatigue, fever, night sweats, or cough can be associated with advanced stages.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:598216","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0020654","ORPHANET_ID__c":"ORPHA:598216","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Carcinoma urotelial de las vías urinarias superiores","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"carcinoma urotelial de las vías urinarias superiores","Spanish_GARD_Synonym__c":"carcinoma de células transicionales de la pelvis y el uréter; carcinoma de células transicionales de las vías urinarias superiores; cu-vus","Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare urinary tract tumor characterized by a malignant neoplasm arising from urothelial cells of the pyelocaliceal cavities and ureter. The tumor may be multifocal and bilateral in some cases and is more common in males than in females. Cigarette smoking and occupational exposure are major risk factors. Patients most commonly present with visible or non-visible hematuria and/or flank pain due to obstruction of the flow of urine by tumor tissue, or (less often) to local tumor growth. Systemic symptoms such as anorexia, weight loss, malaise, fatigue, fever, night sweats, or cough can be associated with advanced stages.","Curated_Disease_Description_Source__c":"ORPHA:598216","GARD_Synonym__c":"renal pelvis and ureter tcc; renal pelvis and ureter transitional cell cancer; renal pelvis and ureter transitional cell carcinoma; renal pelvis and ureter urothelial carcinoma; tcc of renal pelvis and ureter; tcc of the renal pelvis and ureter; transitional cell cancer of renal pelvis and ureter; transitional cell cancer of the renal pelvis and ureter; transitional cell carcinoma of renal pelvis and ureter; transitional cell carcinoma of the pelvis and ureter; transitional cell carcinoma of the upper urinary tract; upper tract urothelial carcinoma; urothelial carcinoma of the renal pelvis and ureter; utuc","Name":"Renal pelvis/ureter urothelial carcinoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Bladder Cancer Canada","Website__c":"https://bladdercancercanada.org/en/"},{"Account_Name__c":"World Bladder Cancer Patient Coalition","Website__c":"https://worldbladdercancer.org/"},{"Account_Name__c":"Bladder Cancer Advocacy Network","Website__c":"https://bcan.org/"},{"Account_Name__c":"American Cancer Society","Website__c":"https://www.cancer.org"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Urogenital Disorders","Tag_Category__c":"Disease Category","category_description":"Urinary and reproductive diseases affect the kidneys, ureters, bladder, urethra, or the reproductive organs.","curated_tag_name":"Urinary and reproductive diseases"},{"Tag_Name__c":"Urologist","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"No data available","Provided_By__c":"ORPHA:598216"}],"External_Identifier_Disease__c":[{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C7716","Source__c":"MONDO:0020654","Xref__c":"C7716"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0020654","Source__c":"GARD:0009376","Xref__c":"MONDO:0020654"},{"URL__c":"https://www.orpha.net/en/disease/detail/598216","Source__c":"MONDO:0020654","Xref__c":"ORPHA:598216"},{"URL__c":"https://www.cancer.gov/types/kidney"},{"URL__c":"https://www.cancer.gov/types/kidney/patient/transitional-cell-treatment-pdq"}],"tags":{"Specialist":["Cancer - Oncologist","Urologist"],"Disease Category":["Cancer","Urogenital Disorders"]},"synonyms":["renal pelvis and ureter tcc"," renal pelvis and ureter transitional cell cancer"," renal pelvis and ureter transitional cell carcinoma"," renal pelvis and ureter urothelial carcinoma"," tcc of renal pelvis and ureter"," tcc of the renal pelvis and ureter"," transitional cell cancer of renal pelvis and ureter"," transitional cell cancer of the renal pelvis and ureter"," transitional cell carcinoma of renal pelvis and ureter"," transitional cell carcinoma of the pelvis and ureter"," transitional cell carcinoma of the upper urinary tract"," upper tract urothelial carcinoma"," urothelial carcinoma of the renal pelvis and ureter"," utuc"]}