{"Name":"Ovarian Brenner tumor","DiseaseID__c":"GARD:0009397","id":9397,"encodedName":"ovarian-brenner-tumor","IsDeleted":false,"Disease_Name_Full__c":"Ovarian Brenner tumor","Xref_IDs__c":"254859006; C3872; C5234884; DOID:2636; MEDGEN:1716777; MONDO:0002370","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":0,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":2,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0002370","Disease_Description__c":"A benign, borderline, or malignant transitional cell neoplasm arising from the ovary. It constitutes between 1% and 2% of all ovarian neoplasms. The average age at presentation is about 50 years. Grossly it is usually unilateral, firm and white or yellowish. Microscopically it consists of solid and cystic nests of epithelial cells resembling transitional epithelium surrounded by an abundant stromal component of dense, fibroblastic nature.","GARD_Name__c":"Ovarian Brenner tumor","GARD_Synonym__c":"brenner neoplasm of ovary; brenner neoplasm of the ovary; brenner tumor of ovary; brenner tumor of the ovary; brenner tumour of ovary; brenner tumour of the ovary; ovarian brenner neoplasm; ovary brenner tumor; ovary brenner tumour","Curated_Disease_Description_Source__c":"GARD:0009397","Curated_Disease_Description__c":"Brenner tumor of the ovary is a solid, abnormal growth (tumor) on the ovary. Most Brenner tumors are not cancerous (benign). These tumors most often occur in women after menopause. They usually do not cause symptoms unless they are very large. When symptoms are present, they may include abdominal pain or vaginal bleeding. The cause of Brenner tumors is unknown. They are usually found by accident during surgery for another reason or during a routine doctor's examination. The diagnosis is made by microscopic examination of a piece of tumor obtained by a surgical biopsy.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0002370","ORPHANET_ID__c":null,"Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":null,"Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":null,"Spanish_GARD_Synonym__c":null,"Category_Linearization__c":null,"icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"Brenner tumor of the ovary is a solid, abnormal growth (tumor) on the ovary. Most Brenner tumors are not cancerous (benign). These tumors most often occur in women after menopause. They usually do not cause symptoms unless they are very large. When symptoms are present, they may include abdominal pain or vaginal bleeding. The cause of Brenner tumors is unknown. They are usually found by accident during surgery for another reason or during a routine doctor's examination. The diagnosis is made by microscopic examination of a piece of tumor obtained by a surgical biopsy.","Curated_Disease_Description_Source__c":"GARD:0009397","GARD_Synonym__c":"brenner neoplasm of ovary; brenner neoplasm of the ovary; brenner tumor of ovary; brenner tumor of the ovary; brenner tumour of ovary; brenner tumour of the ovary; ovarian brenner neoplasm; ovary brenner tumor; ovary brenner tumour","Name":"Ovarian Brenner tumor","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Alianza Iberoamericana de Enfermedades Raras o Poco Frecuentes","Website__c":"https://aliber.org/web/"},{"Account_Name__c":"Federación Mexicana de Enfermedades Raras (FEMEXER)","Website__c":"http://www.femexer.org/"},{"Account_Name__c":"Federación Española de Enfermedades Raras","Website__c":"https://enfermedades-raras.org/"},{"Account_Name__c":"Federación Colombiana de Enfermedades Raras","Website__c":"http://www.fecoer.org"},{"Account_Name__c":"Federación Argentina de Enfermedades Poco Frecuentes","Website__c":"https://fadepof.org.ar/"},{"Account_Name__c":"Asociación Todos Unidos Enfermedades Raras Uruguay","Website__c":"https://atueru.org.uy/"},{"Account_Name__c":"Ovarian Cancer Research Alliance","Website__c":"https://ocrahope.org"},{"Account_Name__c":"National Ovarian Cancer Coalition","Website__c":"https://ovarian.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A2636","Source__c":"MONDO:0002370","Xref__c":"DOID:2636"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C5234884","Source__c":"C5234884","Xref__c":"C5234884"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=1716777","Source__c":"C5234884","Xref__c":"MEDGEN:1716777"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=254859006","Source__c":"MONDO:0002370","Xref__c":"254859006"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C3872","Source__c":"C5234884; MONDO:0002370","Xref__c":"C3872"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0002370","Source__c":"GARD:0009397","Xref__c":"MONDO:0002370"}],"tags":{"Disease Category":["Cancer"]},"synonyms":["brenner neoplasm of ovary"," brenner neoplasm of the ovary"," brenner tumor of ovary"," brenner tumor of the ovary"," brenner tumour of ovary"," brenner tumour of the ovary"," ovarian brenner neoplasm"," ovary brenner tumor"," ovary brenner tumour"],"spanishId":13675,"spanishName":"tumor-de-brenner-del-ovario"}