{"Name":"Variant Creutzfeldt-Jakob disease","DiseaseID__c":"GARD:0009550","id":9550,"encodedName":"variant-creutzfeldt-jakob-disease","IsDeleted":false,"Disease_Name_Full__c":"Variant Creutzfeldt-Jakob disease","Xref_IDs__c":"304603007; A81.01; C0376329; C128438; DOID:5435; MEDGEN:138163; MONDO:0007012; ORPHA:576370","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":2,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":3,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0007012","Disease_Description__c":"A form of Creutzfeldt-Jakob disease that is most commonly contracted after consuming meat from an animal suffering from bovine spongiform encephalopathy.","GARD_Name__c":"Variant Creutzfeldt-Jakob disease","GARD_Synonym__c":"creutzfeldt-jakob variant disease; new variant creutzfeldt-jakob disease; nvcjd - new variant of creutzfeldt-jakob disease; variant mcj; vcjd; vcjd - variant creutzfeldt-jakob disease","Curated_Disease_Description_Source__c":"GARD:0009550","Curated_Disease_Description__c":"\"Variant Creutzfeldt-Jakob disease (vCJD) is a type of Creutzfeldt-Jakob disease (CJD) characterized by early psychiatric symptoms and cognitive decline. All forms of CJD belong to a rare family of progressive neurodegenerative disorders that affect both humans and animals, called prion diseases. The term \"\"prion\"\" refers to abnormal proteins within the brain, called prion proteins. It can result when someone is exposed to contaminated products. The infection responsible for the disease in cows (bovine spongiform encephalitis) is believed to be the same one responsible for vCJD in humans.\"","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":"as an Adult","SourceID__c":"ORPHA:576370","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0007012","ORPHANET_ID__c":"ORPHA:576370","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Variante de la enfermedad de creutzfeldt-jakob","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"variante de la enfermedad de creutzfeldt-jakob","Spanish_GARD_Synonym__c":"vcjd","Category_Linearization__c":"ORPHA:98006","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"\"Variant Creutzfeldt-Jakob disease (vCJD) is a type of Creutzfeldt-Jakob disease (CJD) characterized by early psychiatric symptoms and cognitive decline. All forms of CJD belong to a rare family of progressive neurodegenerative disorders that affect both humans and animals, called prion diseases. The term \"\"prion\"\" refers to abnormal proteins within the brain, called prion proteins. It can result when someone is exposed to contaminated products. The infection responsible for the disease in cows (bovine spongiform encephalitis) is believed to be the same one responsible for vCJD in humans.\"","Curated_Disease_Description_Source__c":"GARD:0009550","GARD_Synonym__c":"creutzfeldt-jakob variant disease; new variant creutzfeldt-jakob disease; nvcjd - new variant of creutzfeldt-jakob disease; variant mcj; vcjd; vcjd - variant creutzfeldt-jakob disease","Name":"Variant Creutzfeldt-Jakob disease","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Creutzfeldt-Jakob Disease Foundation, Inc","Website__c":"https://cjdfoundation.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"},{"Tag_Name__c":"Psychiatry","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"Adult","Provided_By__c":"ORPHA:576370"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=138163","Source__c":"C0376329","Xref__c":"MEDGEN:138163"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/A81.01","Source__c":"MONDO:0007012","Xref__c":"A81.01"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A5435","Source__c":"MONDO:0007012","Xref__c":"DOID:5435"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C128438","Source__c":"C0376329; MONDO:0007012","Xref__c":"C128438"},{"URL__c":"https://www.orpha.net/en/disease/detail/576370","Source__c":"C0376329; MONDO:0007012; ORPHA:576370","Xref__c":"ORPHA:576370"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0376329","Source__c":"C0376329","Xref__c":"C0376329"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=304603007","Source__c":"C0376329; MONDO:0007012","Xref__c":"304603007"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0007012","Source__c":"GARD:0009550","Xref__c":"MONDO:0007012"}],"tags":{"Disease Category":["Neurology"],"Specialist":["Neurology","Psychiatry"]},"synonyms":["creutzfeldt-jakob variant disease"," new variant creutzfeldt-jakob disease"," nvcjd - new variant of creutzfeldt-jakob disease"," variant mcj"," vcjd"," vcjd - variant creutzfeldt-jakob disease"]}