{"Name":"Ovarian gynandroblastoma","DiseaseID__c":"GARD:0009665","id":9665,"encodedName":"ovarian-gynandroblastoma","IsDeleted":false,"Disease_Name_Full__c":"Ovarian gynandroblastoma","Xref_IDs__c":"254867003; C0346178; C3072; C538459; MEDGEN:83412; MONDO:0020540; ORPHA:99914","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":3,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0020540","Disease_Description__c":"A rare neoplasm arising from the ovary. Although it may occur at any age, it is more often seen in young females. Morphologically, it is characterized by a mixture of two cellular populations: well differentiated Sertoli cells and granulosa cells, with the latter constituting at least ten percent of the neoplasm. The vast majority of cases are stage I lesions at presentation and produce either estrogenic or androgenic manifestations. Although it may present as a massive ovarian tumor, it usually follows a benign clinical course. Very rare case reports of testicular lesions morphologically resembling gynandroblastomas are in fact variants of juvenile granulose cell tumor, or Sertoli cell tumor, or a combination of both.","GARD_Name__c":"Ovarian gynandroblastoma","GARD_Synonym__c":"gynandroblastoma; gynandroblastoma of ovary; gynandroblastoma of the ovary","Curated_Disease_Description_Source__c":"MONDO:0020540","Curated_Disease_Description__c":"A rare neoplasm arising from the ovary. Although it may occur at any age, it is more often seen in young females. Morphologically, it is characterized by a mixture of two cellular populations: well differentiated Sertoli cells and granulosa cells, with the latter constituting at least ten percent of the neoplasm. The vast majority of cases are stage I lesions at presentation and produce either estrogenic or androgenic manifestations. Although it may present as a massive ovarian tumor, it usually follows a benign clinical course. Very rare case reports of testicular lesions morphologically resembling gynandroblastomas are in fact variants of juvenile granulose cell tumor, or Sertoli cell tumor, or a combination of both.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":"ORPHA:99914","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0020540","ORPHANET_ID__c":"ORPHA:99914","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Ginandroblastoma","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"ginandroblastoma","Spanish_GARD_Synonym__c":null,"Category_Linearization__c":"ORPHA:250908","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A rare neoplasm arising from the ovary. Although it may occur at any age, it is more often seen in young females. Morphologically, it is characterized by a mixture of two cellular populations: well differentiated Sertoli cells and granulosa cells, with the latter constituting at least ten percent of the neoplasm. The vast majority of cases are stage I lesions at presentation and produce either estrogenic or androgenic manifestations. Although it may present as a massive ovarian tumor, it usually follows a benign clinical course. Very rare case reports of testicular lesions morphologically resembling gynandroblastomas are in fact variants of juvenile granulose cell tumor, or Sertoli cell tumor, or a combination of both.","Curated_Disease_Description_Source__c":"MONDO:0020540","GARD_Synonym__c":"gynandroblastoma; gynandroblastoma of ovary; gynandroblastoma of the ovary","Name":"Ovarian gynandroblastoma","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"National Ovarian Cancer Coalition","Website__c":"https://ovarian.org/"},{"Account_Name__c":"Ovarian Cancer Research Alliance","Website__c":"https://ocrahope.org"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Cancer - Oncologist","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Cancer","Tag_Category__c":"Disease Category","category_description":"Cancer is a disease in which some of the body's cells grow uncontrollably and can spread to other parts of the body.","curated_tag_name":"Cancer"},{"Tag_Name__c":"Urogenital Disorders","Tag_Category__c":"Disease Category","category_description":"Urinary and reproductive diseases affect the kidneys, ureters, bladder, urethra, or the reproductive organs.","curated_tag_name":"Urinary and reproductive diseases"},{"Tag_Name__c":"Obstetrics / Gynecology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Rare gynecological tumor","Tag_Category__c":"Account;Specialist","curated_tag_name":"Gynecological tumors"}],"External_Identifier_Disease__c":[{"URL__c":"https://raresource.nih.gov/diseases/filter/0009665","Source__c":"RareSource"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=254867003","Source__c":"C0346178; MONDO:0020540","Xref__c":"254867003"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0346178","Source__c":"C0346178","Xref__c":"C0346178"},{"URL__c":"https://www.orpha.net/en/disease/detail/99914","Source__c":"C0346178; MONDO:0020540","Xref__c":"ORPHA:99914"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=83412","Source__c":"C0346178","Xref__c":"MEDGEN:83412"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C538459","Source__c":"MONDO:0020540","Xref__c":"C538459"},{"URL__c":"https://evsexplore.semantics.cancer.gov/evsexplore/concept/ncit/C3072","Source__c":"C0346178; MONDO:0020540","Xref__c":"C3072"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0020540","Source__c":"GARD:0009665","Xref__c":"MONDO:0020540"}],"tags":{"Specialist":["Cancer - Oncologist","Obstetrics / Gynecology","Rare gynecological tumor"],"Disease Category":["Cancer","Urogenital Disorders"],"Account":["Rare gynecological tumor"]},"synonyms":["gynandroblastoma"," gynandroblastoma of ovary"," gynandroblastoma of the ovary"]}