{"Name":"Amyopathic dermatomyositis","DiseaseID__c":"GARD:0009907","id":9907,"encodedName":"amyopathic-dermatomyositis","IsDeleted":false,"Disease_Name_Full__c":"Amyopathic dermatomyositis","Xref_IDs__c":"238935002; C0406645; C538250; MEDGEN:96065; MONDO:0043317; ORPHA:645617","USA_Estimate__c":null,"No_of_Specialist_Tagsa__c":5,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":null,"No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":1,"Disease_Characteristics_Score__c":4,"No_of_Age_at_Onset__c":0,"Description_Source__c":"MONDO:0043317","Disease_Description__c":"A form of dermatomyositis characterized by the presence of typicalskin findingswithout muscle weakness.Some of the skinchanges that suggest dermatomyositis include a pink rash on the face, neck, forearms and upper chest; Gottron's papules and heliotrope eyelids. Pruritis and photosensitivity are common, as is scalp inflammation and thinning of the hair.While patients with amyopathic dermatomyositis should not have clinically evident muscle weakness, minor muscle abnormalities may be included.Fatigue is reported in at least 50% of patients. Some cases have beenassociated with internal malignancy and/or interstitial lung disease. Treatment may include sun avoidance, ample use of sunscreen, topical corticosteroids, antimalarial agents, methotrexate, mycophenolate mofetil, or intravenous (IV) immunoglobulin.","GARD_Name__c":"Amyopathic dermatomyositis","GARD_Synonym__c":"dermatomyositis sine myositis","Curated_Disease_Description_Source__c":"MONDO:0043317","Curated_Disease_Description__c":"A form of dermatomyositis characterized by the presence of typical skin finding swithout muscle weakness. Some of the skin changes that suggest dermatomyositis include a pink rash on the face, neck, forearms and upper chest; Gottron's papules and heliotrope eyelids. Pruritis and photosensitivity are common, as is scalp inflammation and thinning of the hair.While patients with amyopathic dermatomyositis should not have clinically evident muscle weakness, minor muscle abnormalities may be included.Fatigue is reported in at least 50% of patients. Some cases have beenassociated with internal malignancy and/or interstitial lung disease. Treatment may include sun avoidance, ample use of sunscreen, topical corticosteroids, antimalarial agents, methotrexate, mycophenolate mofetil, or intravenous (IV) immunoglobulin.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":null,"Age_at_Onset_Snippet_Text__c":null,"SourceID__c":null,"Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Entity","MONDO_ID__c":"MONDO:0043317","ORPHANET_ID__c":"ORPHA:645617","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Dermatomiositis amiopática","Spanish_Description_Source__c":null,"Spanish_Description__c":null,"Spanish_Disease_Name__c":"dermatomiositis amiopática","Spanish_GARD_Synonym__c":"dermatomiositis sin miositis","Category_Linearization__c":"ORPHA:98023","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"A form of dermatomyositis characterized by the presence of typical skin finding swithout muscle weakness. Some of the skin changes that suggest dermatomyositis include a pink rash on the face, neck, forearms and upper chest; Gottron's papules and heliotrope eyelids. Pruritis and photosensitivity are common, as is scalp inflammation and thinning of the hair.While patients with amyopathic dermatomyositis should not have clinically evident muscle weakness, minor muscle abnormalities may be included.Fatigue is reported in at least 50% of patients. Some cases have beenassociated with internal malignancy and/or interstitial lung disease. Treatment may include sun avoidance, ample use of sunscreen, topical corticosteroids, antimalarial agents, methotrexate, mycophenolate mofetil, or intravenous (IV) immunoglobulin.","Curated_Disease_Description_Source__c":"MONDO:0043317","GARD_Synonym__c":"dermatomyositis sine myositis","Name":"Amyopathic dermatomyositis","estimateUsa":""}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"The Arthritis Society","Website__c":"https://arthritis.ca/"},{"Account_Name__c":"Rare Autoinflammatory Conditions Community - UK","Website__c":"https://www.raccuk.com/"},{"Account_Name__c":"The Myositis Association","Website__c":"https://www.myositis.org/"},{"Account_Name__c":"Myositis UK","Website__c":"https://www.myositis.org.uk/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"},{"Tag_Name__c":"Rheumatology","Tag_Category__c":"Specialist"},{"Tag_Name__c":"Nephrology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Kidney diseases affect the kidneys' ability to remove waste and water from blood, create urine, or make certain hormones.","curated_tag_name":"Kidney diseases"},{"Tag_Name__c":"Dermatology","Tag_Category__c":"Account;Disease Category;Specialist","category_description":"Skin diseases, or integumentary system diseases, affect the skin, hair, nails, sweat glands, or oil glands.","curated_tag_name":"Skin diseases"},{"Tag_Name__c":"Neuromuscular medicine","Tag_Category__c":"Specialist","curated_tag_name":"Neuromuscular medicine"}],"External_Identifier_Disease__c":[{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=238935002","Source__c":"C0406645; MONDO:0043317","Xref__c":"238935002"},{"URL__c":"https://www.ncbi.nlm.nih.gov/mesh/C538250","Source__c":"MONDO:0043317","Xref__c":"C538250"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=96065","Source__c":"C0406645","Xref__c":"MEDGEN:96065"},{"URL__c":"https://www.orpha.net/en/disease/detail/645617","Source__c":"MONDO:0043317","Xref__c":"ORPHA:645617"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0406645","Source__c":"C0406645","Xref__c":"C0406645"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0043317","Source__c":"GARD:0009907","Xref__c":"MONDO:0043317"}],"tags":{"Disease Category":["Neurology","Nephrology","Dermatology"],"Specialist":["Neurology","Rheumatology","Nephrology","Dermatology","Neuromuscular medicine"],"Account":["Nephrology","Dermatology"]},"synonyms":["dermatomyositis sine myositis"]}