{"Name":"West-Nile encephalitis","DiseaseID__c":"GARD:0009959","id":9959,"encodedName":"west-nile-encephalitis","IsDeleted":false,"Disease_Name_Full__c":"West-Nile encephalitis","Xref_IDs__c":"392662004; A92.31; C0751583; DOID:2365; MEDGEN:155889; MONDO:0019376; ORPHA:83476","USA_Estimate__c":"5,000","No_of_Specialist_Tagsa__c":4,"No_of_ClinGen_records__c":0,"No_of_GeneReviews__c":0,"No_of_HHS_records__c":0,"World_Estimate__c":"8,000 to 80,000","No_of_HRSA_records__c":0,"Evidence_Based_Score__c":0,"No_of_Disease_Descriptions__c":2,"Disease_Characteristics_Score__c":6,"No_of_Age_at_Onset__c":1,"Description_Source__c":"MONDO:0019376","Disease_Description__c":"An acute arboviral infection caused by a virus of the <i>Flaviviridae</i> family transmitted by an infected mosquito, that is asymptomatic in the majority of cases but that can present in rare occasions with mild flulike symptoms such as low-grade fever, arthralgia, myalgia, and/or rash, or with neurologic manifestations including meningitis, encephalitis with mental confusion or disorientation, tremors and acute flaccid paralysis/poliomyelitis.","GARD_Name__c":"West-Nile encephalitis","GARD_Synonym__c":"west nile encephalitis; west nile fever encephalitis; west nile fever with encephalitis; west nile virus caused infectious encephalitis; west nile virus infectious encephalitis; west-nile fever","Curated_Disease_Description_Source__c":"GARD:0009959","Curated_Disease_Description__c":"West Nile encephalitis is a form of West Nile virus that affects the neurological system. Signs and symptoms may include headache, fever, neck stiffness, disorientation, tremors, seizures, paralysis, or coma. West Nile virus is generally spread to humans by infected mosquitos. West Nile encephalitis, specifically, occurs when the virus crosses the blood-brain barrier and infects the central nervous system. Although West Nile encephalitis can affect anyone, people who are over age 60, have received an organ transplant, or are affected by certain medical conditions such as cancer, diabetes, hypertension, and kidney disease have the highest risk of developing the condition.","Curated_USA_Estimate_Source__c":null,"Curated_USA_Estimate__c":"5,000","Age_at_Onset_Snippet_Text__c":"at any time in life","SourceID__c":"ORPHA:83476","Deprecated__c":"No","Disease_Concept_Type__c":"Rare Disease Grouping","MONDO_ID__c":"MONDO:0019376","ORPHANET_ID__c":"ORPHA:83476","Replaced_By_ID__c":null,"Display_Spanish_Disease_Name__c":"Encefalitis del nilo occidental","Spanish_Description_Source__c":"ORPHA:83476","Spanish_Description__c":"Es una infección arboviral aguda causada por un virus de la familia <i>Flaviviridae</i> transmitido por un mosquito infectado. En la mayoría de los casos es asintomática, aunque puede presentarse excepcionalmente con síntomas leves similares a la gripe, tales como febrícula, artralgia, mialgia y/o erupción cutánea, o con manifestaciones neurológicas que incluyen meningitis, encefalitis con confusión mental o desorientación, temblores y parálisis flácida aguda/poliomielitis.","Spanish_Disease_Name__c":"encefalitis del nilo occidental","Spanish_GARD_Synonym__c":"fiebre del nilo occidental","Category_Linearization__c":"ORPHA:68416","icd10_id__c":null,"mesh_id__c":null,"omim_id__c":null,"snomed_id__c":null,"umls_id__c":null,"GARD_Disease__c":[{"Curated_Disease_Description__c":"West Nile encephalitis is a form of West Nile virus that affects the neurological system. Signs and symptoms may include headache, fever, neck stiffness, disorientation, tremors, seizures, paralysis, or coma. West Nile virus is generally spread to humans by infected mosquitos. West Nile encephalitis, specifically, occurs when the virus crosses the blood-brain barrier and infects the central nervous system. Although West Nile encephalitis can affect anyone, people who are over age 60, have received an organ transplant, or are affected by certain medical conditions such as cancer, diabetes, hypertension, and kidney disease have the highest risk of developing the condition.","Curated_Disease_Description_Source__c":"GARD:0009959","GARD_Synonym__c":"west nile encephalitis; west nile fever encephalitis; west nile fever with encephalitis; west nile virus caused infectious encephalitis; west nile virus infectious encephalitis; west-nile fever","Name":"West-Nile encephalitis","Curated_USA_Estimate__c":"5,000","estimateUsa":"5,000"}],"Organization_Supported_Diseases__c":[{"Account_Name__c":"Encephalitis Society","Website__c":"https://www.encephalitis.info/"},{"Account_Name__c":"Encephalitis411","Website__c":"https://encephalitis411.org/"}],"GARD_Disease_Tag__c":[{"Tag_Name__c":"Infectious Disease","Tag_Category__c":"Disease Category;Specialist","category_description":"Infectious diseases are caused by bacteria, viruses, fungi, or parasites entering the body, multiplying, and spreading illness.","curated_tag_name":"Infectious diseases"},{"Tag_Name__c":"Neurology","Tag_Category__c":"Disease Category;Specialist","category_description":"Neurological diseases affect the brain, spinal cord, cranial nerves, autonomic nerves, or other peripheral nerves.","curated_tag_name":"Neurological diseases"},{"Tag_Name__c":"Rare Viral Disease","Tag_Category__c":"Cause","curated_tag_name":"Viral Infectious Diseases"},{"Tag_Name__c":"Epilepsy","Tag_Category__c":"Account;Specialist","curated_tag_name":"Epilepsy"},{"Tag_Name__c":"Pediatrics","Tag_Category__c":"Specialist"}],"Age_At_Onset__c":[{"Age_At_Onset__c":"All ages","Provided_By__c":"ORPHA:83476"}],"External_Identifier_Disease__c":[{"URL__c":"https://www.orpha.net/en/disease/detail/83476","Source__c":"C0751583; MONDO:0019376; ORPHA:83476","Xref__c":"ORPHA:83476"},{"URL__c":"https://uts.nlm.nih.gov/uts/umls/concept/C0751583","Source__c":"C0751583","Xref__c":"C0751583"},{"URL__c":"https://www.ncbi.nlm.nih.gov/medgen/?term=155889","Source__c":"C0751583","Xref__c":"MEDGEN:155889"},{"URL__c":"https://browser.ihtsdotools.org/?perspective=full&conceptId1=392662004","Source__c":"C0751583; MONDO:0019376","Xref__c":"392662004"},{"URL__c":"https://www.ebi.ac.uk/ols4/ontologies/doid/classes?obo_id=DOID%3A2365","Source__c":"MONDO:0019376","Xref__c":"DOID:2365"},{"URL__c":"http://purl.bioontology.org/ontology/ICD10CM/A92.31","Source__c":"MONDO:0019376","Xref__c":"A92.31"},{"URL__c":"http://purl.obolibrary.org/obo/MONDO_0019376","Source__c":"GARD:0009959","Xref__c":"MONDO:0019376"}],"tags":{"Disease Category":["Infectious Disease","Neurology"],"Specialist":["Infectious Disease","Neurology","Epilepsy","Pediatrics"],"Cause":["Rare Viral Disease"],"Account":["Epilepsy"]},"synonyms":["west nile encephalitis"," west nile fever encephalitis"," west nile fever with encephalitis"," west nile virus caused infectious encephalitis"," west nile virus infectious encephalitis"," west-nile fever"]}