Most people with Majeed syndrome also develop inflammatory disorders of the skin, most often a condition known as Sweet syndrome. The symptoms of Sweet syndrome include fever and the development of painful bumps or blisters on the face, neck, back, and arms.
This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|80%-99% of people have these symptoms|
|Abnormality of bone marrow cell morphology||0005561|
|Chronic recurrent multifocal osteomyelitis||0005901|
|Congenital hypoplastic anemia||0004810|
|Hypochromic microcytic anemia||0004840|
Irregular wide portion of a long bone
|30%-79% of people have these symptoms|
Water retention[ more ]
|Failure to thrive||
Weight faltering[ more ]
|Increased bone mineral density||
Increased bone density
Elevated white blood count
High white blood count
Increased blood leukocyte number[ more ]
Increased spleen size
|5%-29% of people have these symptoms|
Abnormal susceptibility to fractures
Frequent broken bones
Increased bone fragility
Increased tendency to fractures[ more ]
High urine protein levels
Protein in urine[ more ]
|1%-4% of people have these symptoms|
Increased body temperature, episodic
Intermittent fever[ more ]
|Percent of people who have these symptoms is not available through HPO|
Retarded growth[ more ]
|Inflammatory abnormality of the skin||
Making a diagnosis for a genetic or rare disease can often be challenging. Healthcare professionals typically look at a person’s medical history, symptoms, physical exam, and laboratory test results in order to make a diagnosis. The following resources provide information relating to diagnosis and testing for this condition. If you have questions about getting a diagnosis, you should contact a healthcare professional.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
New NCATS Rare Diseases Research Video
December 27, 2017
Rare Disease Day at NIH on March 1, 2018
December 19, 2017
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