The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
|Signs and Symptoms||Approximate number of patients (when available)|
|Inflammation of the large intestine||90%|
|Abnormality of temperature regulation||50%|
|Aplasia/Hypoplasia of the colon||50%|
|Elevated hepatic transaminases||50%|
|Abnormality of the cerebral vasculature||7.5%|
|Abnormality of the myocardium||7.5%|
|Abnormality of the oral cavity||7.5%|
|Abnormality of the pericardium||7.5%|
|Abnormality of the retinal vasculature||7.5%|
|Abnormality of the sacroiliac joint||7.5%|
|Abnormality of thrombocytes||7.5%|
|Biliary tract abnormality||7.5%|
|Inflammatory abnormality of the eye||7.5%|
|Nausea and vomiting||7.5%|
|Neoplasm of the colon||7.5%|
|Recurrent urinary tract infections||7.5%|
|Reduced bone mineral density||7.5%|
|Recurrent aphthous stomatitis||-|
For information on the treatment of Crohn's disease, visit the following links:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK):
Crohn's & Colitis Foundation of America:
Complementary and Alternative Medicine (CAM) for Crohn's disease from the Crohn's & Colitis Foundation of America:
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Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
The Crohn's and Colitis Foundation of America's Information Resource Center (IRC) provides accurate, current, disease-related information to the public, health care professionals, patients and their families. Contact the IRC to understand diagnosis, treatment, and living with Crohn's disease and ulcerative colitis. IRC information specialists are master's level health professionals. They are available Monday through Friday, 9 a.m. to 5 p.m. Eastern Time. Call toll-free 1-888.MY.GUT.PAIN or use the IRC contact form.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
Where can I get a complete list of all genes that have been associated with Crohn's disease? See answer
I have a friend whose husband has Crohn's disease. She may be pregnant and is wondering what the likelihood is that her baby will have this disease. Is there a test that can diagnose Crohn's disease during pregnancy? See answer
How might Crohn's disease be treated? See answer
My father has Crohn's disease for which he has had many surgeries in his lifetime. His brother (my uncle) also had this disease as a young adult. Can you tell me what percent chance I would have of having this disease as well? My fathers other young adult children do not have it as of yet. See answer