I have a two and a half year old daughter diagnosed with biotin thiamine responsive basal ganglia disease one week before she was born. Her older sister had the disease but she died from a viral infection before she was diagnosed. My younger daughter is responding to the treatment of high dosage of biotin and thiamine, and she looks great. Is there any risk that she will not respond to this treatment one day in the future? Is there a possibility she will develop symptoms as seizures and weakness in her muscles as she grows or not necessarily?