The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
| Signs and Symptoms | Approximate number of patients (when available) |
| Thick nail | 5% |
| Autosomal dominant inheritance | - |
| Nail dysplasia | - |
| Slow progression | - |
| Thin nail | - |
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
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A dermatologist recently advised that I have twenty-nail dystrophy. However, when I read about this, it is described as a childhood disorder. Only as an adult have my nails become brittle, with ridges vertical and horizontal. This has even affected my toenails. Also, I am losing a lot of hair. What causes twenty-nail dystrophy? See answer
