Yes. The 22q11.2 duplication can be ‘silent’, or at least there may be no signs or symptoms that make a person stand out from the rest of their family. We know this because some parents and siblings of children with a 22q11.2 duplication have the same duplication, but do not have any obvious unusual features or delayed development - at least not to the point where they need medical or educational intervention. The effect of genetic conditions such as a 22q11.2 duplication on development, health and behavior ranges from being barely noticeable to being obvious and severe.
Last updated: 4/23/2012
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