Is lichen planus pigmentosus a cancerous condition?
Lichen planus pigmentosus (LPP) is not a type of cancer and is generally not associated with an increased risk for cancer. However, one case of LPP has been reported in association with Bazex syndrome and head and neck cancer.
It has been recognized that other types of lichen planus are rarely associated with cancer. For example, bullous lichen planus, a rare form of lichen planus in which blisters form within the characteristic papules, is the subtype that is most frequently linked with cancer. A risk for oral cancer (approximately .5-2%) has also been reported in people affected by oral lichen planus.
Last updated: 4/10/2015
How might lichen planus pigmentosus be treated?
There is currently no consensus about the treatment for lichen planus pigmentosus (LPP). In some cases the symptoms disappear spontaneously within weeks. In all cases, it is recommended to avoid sunlight exposure and to use sunscreen.
Sassolas B, Zagnoli A, Leroy JP, Guillet G. Lichen planus pigmentosus associated with acrokeratosis of Bazex. Clin Exp Dermatol. January 1994; 19(1):70-73.
Supic G, Kozomara R, Zeljic K, Stanimirovic D, Magic M, Surbatovic M, Jovic N, Magic Z. HMGB1 genetic polymorphisms in oral squamous cell carcinoma and oral lichen planus patients. Oral Dis. 2015. January 2015; [Epub ahead of print]:
Han XD, Goh CL. A case of lichen planus pigmentosus that was recalcitrant to topical treatment responding to pigment laser treatment. Dermatol Ther. September-October 2014; 27(5):264-267.
Al-Mutairi N, El-Khalawany M.. Clinicopathological characteristics of lichen planus pigmentosus and its response to tacrolimus ointment: an open label, non-randomized, prospective study. J Eur Acad Dermatol Venereol. May 2010; 24(5):535-540.
Han XK, Goh CL. A case of lichen planus pigmentosus that was recalcitrant to topical treatment responding to pigment laser treatment. Dermatol Ther. Sep-Oct 2014; 27(5):264-7. http://www.ncbi.nlm.nih.gov/pubmed/24796489.