Isolated levocardia is a type of situs inversus where the heart is located in the normal position, but there is a mirror-image reversal of other internal organs. Isolated levocardia may occur alone or with heart defects, heart rhythm abnormalities (sick sinus syndrome or atrioventricular node disorder), spleen defects (absent, underdeveloped, or extra spleen), and intestinal malrotation. Long term outlook varies depending on the presence/absence of associated abnormalities, particularly heart defects. The cause of isolated levocardia is not known. It is not usually associated with chromosome abnormalities.
The overall outlook for infants born with isolated levocardia will vary depending largely on the absence/presence of heart defects. You can find grim estimates for long term survival in dated literature (published in the 1960’s and 70’s). These statistics do not account for mild cases of isolated levocardia diagnosed as a result of improved technologies and detection.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
I am pregnant and my baby has been diagnosed with isolated levocardia with situs inversus. She does not appear to have a heart defect. I've found little information and no support groups for this specific condition. I was given a very grim statistic for her chance of long-term survival. Is this true? Has there been other cases of prenatally diagnosed isolated levocardia with situs inversus? Was MRI or other tests helpful in planning the infants care? See answer