This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|80%-99% of people have these symptoms|
|Aplasia/Hypoplasia of the nipples||
Absent/underdeveloped nipples[ more ]
Abnormality of cognition
Mental impairment[ more ]
|30%-79% of people have these symptoms|
|Abnormality of coagulation||
Abnormal blood clotting
|Cerebral cortical atrophy||0002120|
Increased spleen size
|5%-29% of people have these symptoms|
|Elevated hepatic transaminases||
High liver enzymes
|Percent of people who have these symptoms is not available through HPO|
|Abnormal isoelectric focusing of serum transferrin||0003160|
|Death in infancy||
Lethal in infancy[ more ]
|Failure to thrive||
Weight faltering[ more ]
|Sparse and thin eyebrow||
Thin, sparse eyebrows
Thin eyelashes[ more ]
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Got a Great Research Idea? ‘All of Us’ Wants to Hear It!
January 18, 2018
New NCATS Rare Diseases Research Video
December 27, 2017
Rare Disease Day at NIH on March 1, 2018
December 19, 2017
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know.