The following information may help to address your question:
Common signs and symptoms of wrinkly skin syndrome include wrinkled and inelastic skin on the face, backs of hands, tops of feet, and abdomen, and delayed closure of the fontanel (a baby's "soft spot" on the top of his/her head). Additional signs and symptoms that have been described in individual cases, include:
Small head size (microcephaly)
Unusual facial characteristics
Delayed motor development
Joint laxity, subluxation (a tendon slips out of its normal position)
Online Mendelian Inheritance in Man (OMIM) lists additional signs and symptoms that have been described in people with wrinkly skin syndrome.