Hypertrichosis lanuginosa, acquired

Title

Categories:

Skin Diseases

Summary Summary

The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.

Orpha Number: 2221

Definition

A rare cutaneous paraneoplastic disease characterized by the presence of excessive lanugo-type hair on the glabrous skin of face, neck, trunk and limbs that can be associated with additional clinical features such as burning glossitis, papillary hypertrophy of the tongue, diarrhea, dysgeusia, and/or weight loss. It is associated with lymphoma or cancer of the gastrointestinal system, urinary tract, lung, breast, uterus or ovary.

Visit the Orphanet disease page for more resources.

Last updated: 2/1/2012

Symptoms Symptoms

This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.

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Medical Terms	Other Names	Learn More: HPO ID
80%-99% of people have these symptoms
Abnormal eyebrow morphology	Abnormality of the eyebrow	0000534
Abnormal eyelid morphology	Abnormality of the eyelid Abnormality of the eyelids [ more ]	0000492
Fine hair	Fine hair shaft Fine hair texture Thin hair shaft Thin hair texture [ more ]	0002213
Generalized hirsutism	Excessive hairiness over body	0002230
Hypopigmentation of hair	Loss of hair color	0005599
30%-79% of people have these symptoms
Glossitis	Inflammation of the tongue Smooth swollen tongue [ more ]	0000206
Macroglossia	Abnormally large tongue Increased size of tongue Large tongue [ more ]	0000158
5%-29% of people have these symptoms
Acanthosis nigricans	Darkened and thickened skin	0000956
Chronic diarrhea		0002028
Ichthyosis		0008064
Lymphadenopathy	Swollen lymph nodes	0002716
Neoplasm of the breast	Breast tumor Tumours of the breast [ more ]	0100013
Neoplasm of the respiratory system	Respiratory system tumor	0100606
Ovarian neoplasm	Ovarian tumor	0100615
Poor appetite	Decreased appetite	0004396
Weight loss		0001824

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Last updated: 8/1/2019

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Learn More Learn More

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
Orphanet is a European reference portal for information on rare diseases and orphan drugs. Access to this database is free of charge.

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