This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|80%-99% of people have these symptoms|
Tiredness[ more ]
Elevated white blood count
High white blood count
Increased blood leukocyte number[ more ]
Increased blood neutrophil counts
Skin itching[ more ]
|Restrictive ventilatory defect||
Stiff lung or chest wall causing decreased lung volume
Increased spleen size
|30%-79% of people have these symptoms|
Pain in stomach
Stomach pain[ more ]
Generalized swelling of lymph nodes
Swollen lymph nodes affecting all regions of the body[ more ]
Muscle pain[ more ]
Swelling or irritation of membrane around heart
Inflammation of tissues lining lungs and chest
|5%-29% of people have these symptoms|
|Abnormal circulating lipid concentration||0003119|
|Bone marrow hypocellularity||
Bone marrow failure
|Elevated hepatic transaminase||
High liver enzymes
Inflammation of heart muscle
Recurrent sore throat
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Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis. Please note that the table may not include all the possible conditions related to this disease.
Conditions with similar signs and symptoms from Orphanet
Many other inflammatory, neoplastic, and infectious conditions with a similar presentation must be ruled out in order to diagnose AOSD. Differential diagnoses include infections (endocarditis, occult infections, secondary syphilis, viral rash), malignancies (lymphoma) or autoimmune diseases (such as polyarteritis nodosa, vasculitis, or polymyositis). Genetic counseling (if relevant) AOSD is a sporadic non-inheritable disease and genetic counseling is therefore not needed.
Visit the Orphanet disease page for more information.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
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