There are few reported cases of platelet storage pool deficiency during pregnancy, so management during pregnancy is somewhat unclear.
There is usually no need for intervention during pregnancy, other than recognizing bleeding potential and monitoring platelet count regularly.
Having a planned delivery is extremely important. It appears unnecessary to avoid vaginal delivery (unless there are other complications). However, hemorrhage during labor or surgery should be anticipated and prevented. The prophylactic (preventative) administration of single donor platelets and DDAVP before labor or surgery is potentially life-saving.
Because the condition may be inherited in an autosomal dominant manner, avoiding the use of instruments during delivery may also be recommended if the baby is at risk to be affected.
Pregnant women with platelet storage pool deficiency are strongly encouraged to speak with both their hematologist and obstetrician regarding a planned delivery and having blood products and DDAVP available.
Last updated: 3/9/2016
We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please
Ida Barone, et. al. Management of platelet storage pool disease during pregnancy with recombinant factor VIIa. European Journal of Obstetrics & Gynecology and Reproductive Biology. October, 2013; 170(2):576-577.
Melissa Jewell, Everett F. Magann, Andrew Barr and Ross Baker. Management of platelet storage pool deficiency during pregnancy. Australian and New Zealand Journal of Obstetrics and Gynaecology. March, 2003; 43(2):171-172.