Yes. Although women with Swyer syndrome are infertile, they may become pregnant and carry to term through egg donation and subsequent assisted reproductive technology (ART). Several successful pregnancies in women with Swyer syndrome have been described in the literature. Through hormone management, the uterus can achieve almost normal dimensions and is able to sustain pregnancy. However, it is still unclear whether the anatomic properties of the uterus would permit normal dilatation and labor. C-section has thus been the method of delivery in affected women. Based on reports, those with non-mosaic pure 46,XY gonadal dysgenesis do not appear to be at increased risk for adverse pregnancy outcomes other than those associated with C-section. However, additional reports of pregnancy outcomes in people with Swyer syndrome are needed to expand our knowledge and better define any specific risks.
Last updated: 11/16/2015
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