Adducted thumbs Dundar type

Title

Other Names:

Adducted thumb-club foot syndrome

We add information to this page as we receive questions about this condition. If you have a specific question, contact a GARD Information Specialist.

Symptoms Symptoms

The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.

Signs and Symptoms	Approximate number of patients (when available)
Cryptorchidism	90%
Intellectual disability	5%
Abnormality of the anterior chamber	-
Abnormality of the duodenum	-
Adducted thumb	-
Arachnodactyly	-
Atria septal defect	-
Autosomal recessive inheritance	-
Blue sclerae	-
Brachycephaly	-
Broad forehead	-
Bruising susceptibility	-
Constipation	-
Delayed cranial suture closure	-
Diastasis recti	-
Distal arthrogryposis	-
Facial asymmetry	-
Flat forehead	-
Fragile skin	-
Generalized joint laxity	-
Glaucoma	-
Hearing impairment	-
Hiatus hernia	-
High palate	-
Hydronephrosis	-
Hyperextensible skin	-
Hypertelorism	-
Intestinal malrotation	-
Joint dislocation	-
Joint laxity	-
Large fontanelles	-
Long philtrum	-
Microcornea	-
Microretrognathia	-
Motor delay	-
Muscular hypotonia	-
Myopia	-
Narrow mouth	-
Nephrotic syndrome	-
Pectus excavatum	-
Pneumothorax	-
Posteriorly rotated ears	-
Protruding ear	-
Recurrent skin infections	-
Retinal detachment	-
Scarring	-
Scoliosis	-
Strabismus	-
Talipes equinovarus	-
Telecanthus	-
Umbilical hernia	-
Ventriculomegaly	-

Last updated: 9/1/2016

Research Research

Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.

Clinical Research Resources

The University of California San Francisco Limb Study is researching the genetic causes of limb malformations. They are looking for participants who only have problems with their limbs, such as fused or webbed fingers/toes, more than 5 fingers/toes, less than 5 fingers/toes, split hand and foot also called ectrodactyly, short fingers/toes, bent pinky fingers, extra long fingers, flexed fingers, club foot, etc. Visit the study’s website to learn more about who is eligible to take part in this study.

Living With Living With

Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.

Genetics Resources

To find a medical professional who specializes in genetics, you can ask your doctor for a referral or you can search for one yourself. Online directories are provided by GeneTests, the American College of Medical Genetics, and the National Society of Genetic Counselors. If you need additional help, contact a GARD Information Specialist. You can also learn more about genetic consultations from Genetics Home Reference.

Learn More Learn More

These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.

In-Depth Information

The Monarch Initiative brings together data about this condition from humans and other species to help physicians and biomedical researchers. Monarch’s tools are designed to make it easier to compare the signs and symptoms (phenotypes) of different diseases and discover common features. This initiative is a collaboration between several academic institutions across the world and is funded by the National Institutes of Health. Visit the website to explore the biology of this condition.
Online Mendelian Inheritance in Man (OMIM) is a catalog of human genes and genetic disorders. Each entry has a summary of related medical articles. It is meant for health care professionals and researchers. OMIM is maintained by Johns Hopkins University School of Medicine.
PubMed is a searchable database of medical literature and lists journal articles that discuss Adducted thumbs Dundar type. Click on the link to view a sample search on this topic.