In most instances, only one individual in a family is affected by Worster-Drought syndrome (WDS). Approximately 15% of individuals with WDS may develop this condition due to a genetic cause; this percentage is based on descriptions of a few families with multiple affected relatives. The particular gene or genes associated with WDS have not been identified and the pattern of inheritance in not known, which makes it difficult to determine the exact chance that a relative of an individual with WDS could also be affected.
Last updated: 5/2/2013
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Clark M, Harris R, Jolleff N, Price K, Neville BG. Worster-Drought syndrome: poorly recognized despite severe and persistent difficulties with feeding and speech. Developmental medicine and child neurology. 2010; 52:27-32. http://www.ncbi.nlm.nih.gov/pubmed/19824895. Accessed 5/1/2013.
Clark M, Neville BG. Familial and genetic associations in Worster-Drought syndrome and perisylvian disorders. American journal of medical genetics Part A. 2008; 146A:35-42. http://www.ncbi.nlm.nih.gov/pubmed/17994559. Accessed 5/1/2013.