This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|80%-99% of people have these symptoms|
|30%-79% of people have these symptoms|
|Clinodactyly of the 5th finger||
Permanent curving of the pinkie finger
Abnormality of cognition
Mental impairment[ more ]
Prominent eye folds[ more ]
Low or weak muscle tone
|Specific learning disability||0001328|
Increased body height
|5%-29% of people have these symptoms|
Excessive, persistent worry and fear
|Attention deficit hyperactivity disorder||
Attention deficit disorder
Attention deficit-hyperactivity disorder
Childhood attention deficit/hyperactivity disorder[ more ]
Widely spaced eyes[ more ]
Joints move beyond expected range of motion
|Multicystic kidney dysplasia||0000003|
Absent/underdeveloped kidney[ more ]
Previous menstrual periods stop
|Upslanted palpebral fissure||
Upward slanting of the opening between the eyelids
Related diseases are conditions that have similar signs and symptoms. A health care provider may consider these conditions in the table below when making a diagnosis. Please note that the table may not include all the possible conditions related to this disease.
Conditions with similar signs and symptoms from Orphanet
Differential diagnosis prior to definitive karyotype results includes fragile X syndrome, tetrasomy X, pentasomy X, and Turner syndrome mosaicism (see these terms).
Visit the Orphanet disease page for more information.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
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Hello my daughter has trisomy x and so far is doing well except for a being significantly underweight. Is there a correlation with difficulty to gain weight and trisomy x? See answer
My elementary school-aged granddaughter was recently diagnosed with 47 XXX syndrome. In addition, she has Attention deficit hyperactivity disorder (ADHD). I was wondering what the possible relationship might be, if any, between ADHD and the behavior problems associated with 47 XXX syndrome. Is it possible that her behavioral concerns are resulting from her chromosome abnormality and not ADHD? See answer
I was wondering if there is a treatment or if there are any in development. Also, is there still research being done about triple X? Are there any tests that need to be done besides a blood test? Are there any physical or mental characteristics associated with the disorder? See answer
Does 47 XXX syndrome affect fertility? What are the chances for a woman with 47 XXX syndrome to have a child with the same condition? See answer