Are there risks associated with pregnancy after repair of an ostium secundum atrial septal defect?
Atrial septal defect (ASD) is the most common repaired or unrepaired lesion in pregnant women with congenital heart disease. Once an atrial septal defect (ASD) is closed and there is no residual hole, the risk of maternal cardiac complications is very low. The only circumstance in which pregnancy is not advised in women with ASDs (whether repaired or not) is the presence of severe pulmonary arterial hypertension. No significantly increased risk of fetal complications in patients with repaired ASDs was reported in a large, multinational study published in 2011.
In order to make informed pregnancy decisions, women with congenital heart disease should have a preconception (pre-pregnancy) evaluation by a cardiologist with expertise in pregnancy and congenital heart disease. Women with congenital heart disease should also be offered fetal echocardiography in the 19th to 22nd week of pregnancy to evaluate the fetal heart.
Last updated: 8/4/2016
Is an ostium secundum atrial septal defect inherited?
Most atrial septal defects (ASDs) occur sporadically (by chance), though familial transmission has also been reported. Some cases appear to have autosomal dominant inheritance. Some genetic syndromes with skeletal abnormalities associated with ASD also have autosomal dominant inheritance.
It is not possible to predict whether the child of a person with an ASD, or another congenital heart defect, will be affected. Because of the possibility that it can be familial, the family and medical history should be carefully evaluated by a cardiologist or a genetics professional. These specialists can address questions and concerns and assess recurrence risks.
Additionally, women with congenital heart disease (or whose partner has congenital heart disease) should be offered fetal echocardiography in the 19th to 22nd week of pregnancy to evaluate the fetal heart.
Last updated: 8/5/2016
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