My mother has MS similar to balo disease and now is under control with Methylprednisolone treatment but cannot get cured. Just want to check whether any one has experience about this MS and whether Interferon will work.
date there have been no controlled treatment studies for tumefactive
multiple sclerosis. As a result, treatment decisions are largely based
on a doctor's experience and information from single case reports.
In a small number of cases, people with tumefactive multiple sclerosis
have minimal to no symptoms. A reasonable approach of care in these
cases is to monitor without treatment.
In most cases the
size of the lesion and resulting symptoms prompts treatment with
corticosteroids. As with other forms of multiple sclerosis,
corticosteroids (for example, intravenous methylprednisolone) should be the first
line of treatment. If corticosteroids are not effective, plasma exchange is tried. Another second line treatment that has been tried
with some success is Rituximab.
Last updated: 5/19/2016
Do people with controlled tumefactive multiple sclerosis benefit from disease modifying therapies, such as interferons?
modifying therapies (for example, interferon-β and glatiramer acetate)
are most arguably appropriate for people with tumefactive multiple
sclerosis who meet multiple sclerosis (MS) diagnostic
criteria, or who have characteristics suggesting that they'll likely
convert to MS, or those who have particularly severe or disabling
tumefactive multiple sclerosis, or those who continue to experience
symptoms, or perhaps those who have worsening lesions on imaging
tests. This is because some people with tumefactive multiple sclerosis
do not experience a second attack, and for those that do, there is often
already a delay before their second attack (as compared to relapsing-remitting MS
Careful thought is needed to weigh the risk for adverse drug effects versus the potential benefit of delaying or
preventing a second attack of tumefactive multiple sclerosis.
Lastly, certain MS drugs, such as Fingolimod, may be contraindicated. Case reports suggest that this drug may actually trigger tumefactive
negative and beneficial responses have been reported with
Last updated: 5/19/2016
We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please