Signs and symptoms may differ depending on the form of BL and the organs or body systems involved. When it spreads, weakness and fatigue often develop. Lymphoma cells may build up in the
The exact cause of BL is not known. EBV infection appears to play a role in virtually all cases of endemic (African) BL, and a minority of sporadic and immunodeficiency-associated BL. While acquired (not
Without timely treatment, BL is rapidly fatal. Treatment involves intensive
This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|30%-79% of people have these symptoms|
|Abnormal lactate dehydrogenase activity||0045040|
|Abnormality of bone marrow
High blood uric acid level
Tumor of mouth
|5%-29% of people have these symptoms|
Pain in stomach
Stomach pain[ more ]
|Abnormality of the liver||
Liver abnormality[ more ]
|Abnormality of the
Abnormal lymph node histology
|Abnormality of the ovary||
Abnormality of the ovaries
|Abnormality of the pancreas||0001732|
|Abnormality of the spleen||0001743|
|Decreased proportion of CD4-positive T cells||0005407|
Intestinal blockage[ more ]
|Nausea and vomiting||0002017|
|Percent of people who have these symptoms is not available through HPO|
Making a diagnosis for a genetic or rare disease can often be challenging. Healthcare professionals typically look at a person’s medical history, symptoms, physical exam, and laboratory test results in order to make a diagnosis. The following resources provide information relating to diagnosis and testing for this condition. If you have questions about getting a diagnosis, you should contact a healthcare professional.
If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. You may find these specialists through advocacy organizations, clinical trials, or articles published in medical journals. You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments.
If you can’t find a specialist in your local area, try contacting national or international specialists. They may be able to refer you to someone they know through conferences or research efforts. Some specialists may be willing to consult with you or your local doctors over the phone or by email if you can't travel to them for care.
You can find more tips in our guide, How to Find a Disease Specialist. We also encourage you to explore the rest of this page to find resources that can help you find specialists.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
My boyfriend was diagnosed with Burkitt lymphoma at the age of 22 after experiencing night sweats, weight loss, pain in his jaw and a bad back. He underwent 4 months of chemo and intrathecal chemo and has been in remission. As Burkitt is so rare, there is a lack of research determining whether the treatment is curative or palliative and I want to know what the chances are that it will return. I am also concerned as to whether it is hereditary. His brother was born with CHARGE syndrome, a rare genetic disorder that affects learning, growth and the ability to hear. See answer