The information I have read said that most infections occur in younger people. I have not had any major problems until now at 56 years of age. Should I be under a doctors care regularly? Am I a candidate for disability?
Is it uncommon for symptoms of chronic granulomatous disease to begin in adulthood?
Signs and symptoms of chronic granulomatous disease usually present in childhood, often before the age of five. However, a growing number of people with this condition are being diagnosed in later childhood or adulthood. This may be due in part to better detection of milder cases.
Last updated: 2/11/2015
How might chronic granulomatous disease be treated?
Chronic granulomatous disease is usually managed with antibiotic and antifungal medications to treat and prevent infection. Corticosteriods may be used to shrink granulomas (areas of inflamed tissue). Treatment may also include a medication called Actimmune (also known as interferon gamma-1b). Actimmune is a man-made version of a substance normally produced by the body's immune cells and has been shown to decrease the frequency of severe infections in people with chronic granulomatous disease.
Early diagnosis of infection is very important, so people with chronic granulomatous disease are generally followed closely by a medical professional. The frequency of follow-up will depend on the severity of the condition.
A bone marrow transplant (allogeneic hematopoietic stem cell transplantation or HSCT) may be used to treat and possibly cure chronic granulomatous disease, however HSCT has serious risks including the possibility of severe disability or death. Although the risks associated with HSCT are decreasing due to medical advances, HSCT is usually only considered for those severely affected by chronic granulomatous disease.
Medical researchers believe gene therapy also holds great promise as a future cure, but more clinical studies are needed to determine if gene therapy will be both safe and effective for those with chronic granulomatous disease. As medical researchers better understand chronic granulomatous disease, new treatments that help control the immune system (immunomodulatory agents) may also become available.
Last updated: 12/19/2016
Are people with chronic granulomatous disease eligible for disability?
Eligibility for disability depends not on diagnosis, but degree of condition involvement and impairment. For further information regarding your eligibility, you may find it helpful to speak with a social worker at your local hospital. In addition, you may benefit from visiting Disability.gov, which provides quick and easy access to comprehensive information about disability programs, services, laws and benefits.
Last updated: 2/11/2015
We hope this information is helpful. We strongly recommend you discuss this information with your doctor. If you still have questions, please