The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
|Signs and Symptoms||Approximate number of patients (when available)|
|Decreased antibody level in blood||90%|
|Recurrent respiratory infections||90%|
|Abnormality of the bronchi||50%|
|Elevated hepatic transaminases||50%|
|Gastrointestinal stroma tumor||7.5%|
|Neoplasm of the stomach||7.5%|
|Restrictive ventilatory defect||7.5%|
|Autosomal recessive inheritance||-|
|Impaired T cell function||-|
|Recurrent bacterial infections||-|
|Recurrent otitis media||-|
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD. Suggest an organization to add.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
Workshop on Registries for Primary Immunodeficiency Diseases Tuesday, November 19, 1996
Location: NIH Campus, Bethesda, MD
Contact: Dr. Howard Dickler(301) 496-7104
Co-funding Institute(s): National Institute of Allergy and Infectious Diseases
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
I have CVID and I am currently expecting my second child. I breastfed my first for 6 months, however, this was before my diagnosis. Is it worth me feeding a second time? Will the Ig from my replacement therapy be passed on to my child in my milk, or would they get more nutrition with formula milk? See answer
My daughter was diagnosed late at 38 and she is now almost 45. She now only has a little energy for a few hours a day. What is the life expectancy? See answer
Does CVID affect pregnancy? Is there any risk in conceiving, or carrying a baby to full term? See answer
Do you have any information about CVID? How does one contract this disease? Is there any cure or treatment for this disease? My husband has been told he has this disease and has been getting IVIG infusions, but he seems to be getting sicker every time he goes. The last two times he had to have 2 units of red blood. Is this normal? See answer