The signs and symptoms of Cushing's syndrome may include:
The Human Phenotype Ontology (HPO) provides the following list of features that have been reported in people with this condition. Much of the information in the HPO comes from Orphanet, a European rare disease database. If available, the list includes a rough estimate of how common a feature is (its frequency). Frequencies are based on a specific study and may not be representative of all studies. You can use the MedlinePlus Medical Dictionary for definitions of the terms below.
|Signs and Symptoms||Approximate number of patients (when available)|
|Abnormality of adipose tissue||90%|
|Reduced bone mineral density||50%|
|Abnormal renal physiology||7.5%|
|Abnormality of lipid metabolism||7.5%|
|Abnormality of the gastric mucosa||7.5%|
|Neoplasm of the adrenal gland||7.5%|
|Telangiectasia of the skin||7.5%|
|Autosomal dominant inheritance||-|
|Decreased circulating ACTH level||-|
|Increased circulating cortisol level||-|
|Macronodular adrenal hyperplasia||-|
|Skeletal muscle atrophy||-|
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Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Nonprofit support and advocacy groups bring together patients, families, medical professionals, and researchers. These groups often raise awareness, provide support, and develop patient-centered information. Many are the driving force behind research for better treatments and possible cures. They can direct people to research, resources, and services. Many groups also have experts who serve as medical advisors. Visit their website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD. Suggest an organization to add.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
17th Adrenal Cortex Conference
Tuesday, March 29, 2016 -
Thursday, March 31, 2016
Location: Boston, MA
Description: Since 1984 the Conference on the Adrenal Cortex has provided an exciting combination of science and resources for basic and clinical scientists. The 2016 conference will continue the tradition by including renowned speakers who will cover the latest research on adrenal development, hormone signaling, steroidogenesis, adrenal insufficiency, primary aldosteronism, Cushing’s syndrome and adrenal cancer. As in previous meetings, the Keith L. Parker Memorial Lecture will be awarded to an international leader for their contributions to adrenal research.
Contact: Dr. Maria L. Dufau(301) firstname.lastname@example.org
International Adrenal Cortex Conference “Adrenal 2010”
Wednesday, June 16, 2010 -
Friday, June 18, 2010
Location: San Diego, California
Description: This conference provided a forum for both new and established investigators to present their most recent work, highlighting new findings relevant to adrenal physiology, biochemistry and molecular biology, genetics, and medicine. It was anticipated that these discoveries would provide a framework for further understanding of the function of the adrenal gland and its contributions to health and disease.
Contact: Maria L. Dufau, M.D., Ph.D., email@example.com firstname.lastname@example.org
Co-funding Institute(s): National Institute of Child Health and Human Development, Office of Rare Diseases Research
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My sister has been diagnosed with Cushing's syndrome. Is this disease hereditary? See answer