This table lists symptoms that people with this disease may have. For most diseases, symptoms will vary from person to person. People with the same disease may not have all the symptoms listed. This information comes from a database called the Human Phenotype Ontology (HPO) . The HPO collects information on symptoms that have been described in medical resources. The HPO is updated regularly. Use the HPO ID to access more in-depth information about a symptom.
|Medical Terms||Other Names||
|80%-99% of people have these symptoms|
|Exocrine pancreatic insufficiency||0001738|
Decreased immune function
|Recurrent respiratory infections||
Frequent respiratory infections
Multiple respiratory infections
respiratory infections, recurrent
Susceptibility to respiratory infections[ more ]
|5%-29% of people have these symptoms|
|Percent of people who have these symptoms is not available through HPO|
Permanent enlargement of the airways of the lungs
|Chronic lung disease||0006528|
|Elevated sweat chloride||0012236|
|Failure to thrive||
Weight faltering[ more ]
Elevated urine calcium levels
|Recurrent bronchopulmonary infections||0006538|
More information about genetic testing for cystic fibrosis is available on The National Human
Learn more orphan products.
If you need medical advice, you can look for doctors or other healthcare professionals who have experience with this disease. You may find these specialists through advocacy organizations, clinical trials, or articles published in medical journals. You may also want to contact a university or tertiary medical center in your area, because these centers tend to see more complex cases and have the latest technology and treatments.
If you can’t find a specialist in your local area, try contacting national or international specialists. They may be able to refer you to someone they know through conferences or research efforts. Some specialists may be willing to consult with you or your local doctors over the phone or by email if you can't travel to them for care.
You can find more tips in our guide, How to Find a Disease Specialist. We also encourage you to explore the rest of this page to find resources that can help you find specialists.
Research helps us better understand diseases and can lead to advances in diagnosis and treatment. This section provides resources to help you learn about medical research and ways to get involved.
Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services. Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.
Living with a genetic or rare disease can impact the daily lives of patients and families. These resources can help families navigate various aspects of living with a rare disease.
These resources provide more information about this condition or associated symptoms. The in-depth resources contain medical and scientific language that may be hard to understand. You may want to review these resources with a medical professional.
NCATS Rare Diseases Are Not Rare! Challenge
October 9, 2018
The NIH Undiagnosed Diseases Network Expands
September 26, 2018
New FDA Approved Orphan Drugs
May 31, 2018
2017 Million Dollar Bike Ride Pilot Grant Program
August 30, 2017
2016 Million Dollar Bike Ride Pilot Grant Program
August 15, 2016
Questions sent to GARD may be posted here if the information could be helpful to others. We remove all identifying information when posting a question to protect your privacy. If you do not want your question posted, please let us know. Submit a new question
I have Russell-Silver syndrome (RSS) and my boyfriend has cystic fibrosis. I recently found out that both are caused by mutations of chromosome 7. Does that mean that I could be a carrier of cystic fibrosis (CF)? See answer
My child is 11 years-old and has many of the symptoms of cystic fibrosis. She'll be undergoing testing next week. How common is it to be diagnosed with cystic fibrosis this late in life? See answer
Are carriers of cystic fibrosis at a higher risk for other health conditions? See answer
We have been told that my newborn grandson has been classified as a carrier for cystic fibrosis. I know that if both parents have the defective gene, the child has a 25 percent chance of actually getting CF, and a 50 percent chance of being a carrier. My question is, can the child be a carrier if only one parent has the defective gene?
Thank you. See answer
What are the current genetic tests for cystic fibrosis? How much do they cost? See answer
Is there new information on genes that cause cystic fibrosis? If cystic fibrosis testing was done by amniocentesis 6 years ago, have there been any new findings since then? See answer
Where can I get information on cystic fibrosis carrier screening and the official recommendations for pregnant women? See answer
Could you please send any and all information on Cystic Fibrosis. One of the staff members has a child with CF and stated the child is not suppose to be in the same classroom with another child with CF. I would like to know why that is? I assume it is related to the altered immunity state. How does this work? What do they do to address this problem? See answer